Suppliers for Lab ELISAs Our used monoclonals in Pubmed.
Compare polyclonal lab reagents for research
Suppliers for Lab reagents Our used recombinants in Pubmed.
monoclonal Lab Reagents for Research
Assay Lab Reagents for Research
Promoted source Our used References in Pubmed.
Chagas Disease Serological Test Performance
Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in the chronic phase requires positive results from two different IgG serological tests. Three enzyme-linked immunosorbent assays (ELISAs) (Hemagen, Ortho, and Wiener) and one rapid test (InBios) are FDA cleared, but comparative data in U.S. populations are sparse. We evaluated 500 seropositive and… Continue reading
Pancreas-type ribonucleasen zijn
Pancreas-type ribonucleasen zijn secretoire enzymen die de splitsing van RNA katalyseren. Recente inspanningen hebben de homologen van koe (RNase A) en mens (RNase 1) begiftigd met toxiciteit voor kankercellen, wat heeft geleid tot een klinische proef. De basis voor de selectieve toxiciteit van ribonucleasevarianten voor kankercellen versus niet-kankercellen is echter onduidelijk. Een screening op RNase… Continue reading
Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS
The identification and management of monoclonal antibody (mAb) vital high quality attributes (CQAs) is a key element of high quality by design (QbD). In this work, fast peptide mapping and native intact cost variants evaluation have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis – mass spectrometry (CE-MS) platform.… Continue reading
Orally administered anti-eotaxin-1 monoclonal antibody is biologically active in the gut and alleviates immune-mediated hepatitis: A novel anti-inflammatory personalized therapeutic approach
Personalized therapies are designed to optimize the safety-to-efficacy ratio by deciding on sufferers with larger response charges based mostly on particular biomarkers. Inflammation performs an important position in the pathogenesis of non-alcoholic steatohepatitis (NASH), a standard liver dysfunction. Eotaxin-1 performs a task in innate and adaptive immune responses. High eotaxin-1 ranges are related to diabetes… Continue reading
Preferential Light-Chain Labeling of Native Monoclonal Antibodies Improves the Properties of Fluorophore Conjugates
Site particular labeling strategies have important potential to boost the properties of antibody conjugates. While studied extensively in the context of antibody-drug conjugates (ADCs), few research have examined the influence of homogenous labeling on the properties of antibody-fluorophore conjugates (AFCs). We report the utility of pentafluorophenyl (PFP) esters, which had beforehand been proven to be… Continue reading
Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations
Tunable resistive pulse sensing (TRPS, qNano Gold, IZON Ltd.) was investigated as a way to quantify submicron particles (SMPs) between 0.1 and 1 µm in options of biopharmaceuticals. To cut back pattern dilution, a spiking-in method was used so as to add the applicable quantity of electrolytes required for the measurement. For right particle quantification,… Continue reading