Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations

Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations

Posted on by Cody

Tunable resistive pulse sensing (TRPS, qNano Gold, IZON Ltd.) was investigated as a way to quantify submicron particles (SMPs) between 0.1 and 1 µm in options of biopharmaceuticals. To cut back pattern dilution, a spiking-in method was used so as to add the applicable quantity of electrolytes required for the measurement. For right particle quantification, an electrolyte focus of at the very least 50 mM sodium chloride was wanted. Intra- and inter-nanopore variability had been beneath 5% for measurement and beneath 10% for focus measurements when analyzing polystyrene normal beads.

Submicron particle counts in a stir pressured IgG1 monoclonal antibody formulation resulted in a non-symmetrical, nearly bell-shaped measurement distribution with a most at 250 nm when utilizing a NP300 nanopore (IZON Ltd.). It was proven that particle counts are closely underestimated beneath 250 nm, and due to this fact it’s endorsed to quantify particle counts by TRPS in samples with heterogeneous particle measurement distributions (e.g., biopharmaceuticals) solely ranging from the most of the histogram in the direction of the higher restrict of detection.

Extremely drug-resistant (XDR) Acinetobacter baumannii is a infamous and ceaselessly encountered pathogen demanding novel therapeutic interventions. An preliminary monoclonal antibody (MAb), C8, raised in opposition to A. baumannii capsule proved a extremely efficient remedy in opposition to a minority of medical isolates. To overcome this limitation, we broadened protection by creating a second antibody for use in a mix routine.

Retrospective immunohistochemical investigation on dolphin morbillivirus an infection by evaluating the efficiency of heterologous monoclonal and polyclonal antibodies – Short communication

Dolphin morbillivirus (DMV) is a pathogen of nice concern in free-ranging cetaceans. Confirmation and staging of morbillivirus infections depend on histology and immunohistochemistry (IHC), following molecular detection. As at the current time no particular antibodies (Abs) in opposition to DMV can be found, two heterologous Abs have been used worldwide for the examinations of morbillivirus infections of cetaceans. One is a monoclonal Ab (MoAb) ready in opposition to the N protein of canine distemper virus (CDV), whereas the different is a polyclonal Ab raised in rabbits in opposition to rinderpest virus (RPV).

Both Abs are recognized to point out cross-reactivity with DMV. In this examine we in contrast the labelling high quality and the neuroanatomical distribution of staining with these two Abs by means of IHC evaluation. To this finish, serial sections of the goal organs from ten free-ranging stranded cetaceans, beforehand recognized as being contaminated with DMV by PCR and/or serology, had been subjected to IHC. The mind, lungs and lymph nodes of one animal had been discovered to be constructive with each Abs. From two different animals, the mind and the spleen, respectively, examined constructive solely with the polyclonal Ab. In the constructive mind tissues, multifocal immunostaining was noticed, with comparable staining location and extent, with the two antibodies examined.

Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations

Our outcomes counsel that the polyclonal anti-RPV Ab may need a stronger binding exercise to DMV than the anti-CDV MoAb. Nevertheless, the elaboration and use of particular anti-DMV Abs is perhaps important to ensure conclusive outcomes in diagnostic and pathogenetic investigations. We report the isolation of two human IgG1k monoclonal antibodies (mAbs) directed in opposition to the SARS-CoV-2 spike protein. These mAbs had been remoted from two donors who had recovered from COVID-19 an infection throughout the first pandemic peak in the Lombardy area of Italy, the first European and initially most affected area in March 2020.

We used the technique of EBV immortalization of purified reminiscence B cells and supernatant screening with a spike S1/2 assay for mAb isolation. This technique allowed fast isolation of clones, with one donor exhibiting about 7% of clones constructive in opposition to spike protein, whereas the different donor didn’t produce constructive clones out of 91 examined. RNA was extracted from constructive clones 39-47 days post-EBV an infection, permitting VH and VL sequencing. The identical clones had been sequenced once more after an extra 100 days in tradition, exhibiting that no mutation had taken place throughout in vitro growth.

Effects of Mild and Moderate Monoclonal Antibody Dose on Inflammation, Bone Loss, and Activation of the Central Nervous System in a Female Collagen Antibody-induced Arthritis Mouse Model

Induction of extreme inflammatory arthritis in the collagen antibody-induced arthritis (CAIA) murine mannequin causes in depth joint injury and pain-like habits compromising evaluation. While delicate fashions are much less extreme, their diminished, variable penetrance makes evaluation of remedy efficacy troublesome. This examine aimed to check macroscopic and microscopic modifications in the paws, together with central nervous system activation between a light and average CAIA mannequin. Balb/c mice (n=18) had been allotted to regulate, delicate, and average CAIA teams.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-500ug 500ug
EUR 2106
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-1mg
QP5624-ec-1mg 1mg
EUR 1958.4

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-100ug
QP5624-ec-100ug 100ug
EUR 489.6

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-10ug
QP5624-ec-10ug 10ug
EUR 240

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-200ug
QP5624-ec-200ug 200ug
EUR 760.8

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-500ug
QP5624-ec-500ug 500ug
EUR 1272

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-50ug
QP5624-ec-50ug 50ug
EUR 315.6

Angiotensinogen (1-14) , Rat
5-00699 4 x 5mg Ask for price

Angiotensinogen (1- 13)
5-00696 4 x 5mg Ask for price

Angiotensinogen Peptide
20-abx265209
  • EUR 678.00
  • EUR 1144.80
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx265535
  • EUR 661.20
  • EUR 1111.20
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx266414
  • EUR 627.60
  • EUR 1045.20
  • EUR 460.80
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx266467
  • EUR 661.20
  • EUR 1111.20
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen (1-14), human
5-00697 4 x 5mg Ask for price

Angiotensinogen (1-14), human
HY-P1486 10mg
EUR 763.2

Angiotensinogen antibody
10R-A130a 200 ul
EUR 678
Description: Mouse monoclonal Angiotensinogen antibody

Angiotensinogen antibody
10R-A131a 200 ul
EUR 548.4
Description: Mouse monoclonal Angiotensinogen antibody

Angiotensinogen antibody
70R-12752 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody

Angiotensinogen antibody
70R-13411 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody

Angiotensinogen Antibody
49159-100ul 100ul
EUR 399.6

Angiotensinogen Antibody
49159-50ul 50ul
EUR 286.8

Angiotensinogen Antibody
R32681 100ug
EUR 356.15
Description: AGT (Angiotensinogen), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Angiotensinogen Antibody
RQ6926 100 ug
EUR 356.15
Description: AGT (ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Angiotensinogen Antibody
RQ4852 100ul
EUR 356.15
Description: Angiotensinogen is an essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [UniProt]

Angiotensinogen (1-14), Porcine
5-00698 4 x 5mg Ask for price

Human Angiotensinogen (AGT)
1-CSB-EP001463HU1
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Angiotensinogen(AGT),partial expressed in E.coli

Angiotensinogen Rabbit mAb
A11689-100ul 100 ul
EUR 492

Angiotensinogen Rabbit mAb
A11689-200ul 200 ul
EUR 685.2

Angiotensinogen Rabbit mAb
A11689-20ul 20 ul
EUR 265.2

Angiotensinogen Rabbit mAb
A11689-50ul 50 ul
EUR 344.4

Angiotensinogen (AGT) Antibody
20-abx242324
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx230393-100ug 100 ug
EUR 610.8

Angiotensinogen (AGT) Antibody
abx230394-100ug 100 ug
EUR 577.2

Angiotensinogen (AGT) Antibody
abx230395-100ug 100 ug
EUR 577.2

Angiotensinogen (AGT) Antibody
20-abx241726
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx241946
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx241947
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx175400
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Angiotensinogen (AGT) Antibody
20-abx171240
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Angiotensinogen (AGT) Antibody
20-abx214416
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx211344
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx322250
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx110982
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx033720-400ul 400 ul
EUR 627.6

Angiotensinogen (AGT) Antibody
abx033720-80l 80 µl
EUR 343.2

Angiotensinogen (AGT) Antibody
abx033721-400ul 400 ul
EUR 627.6

Angiotensinogen (AGT) Antibody
abx033721-80l 80 µl
EUR 343.2

Angiotensinogen (AGT) Antibody
20-abx101137
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101138
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101139
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101140
  • EUR 393.60
  • EUR 978.00
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx128540
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen, Human Plasma
ATN15-N-100 100 ug
EUR 270

Angiotensinogen (AGT) Antibody
20-abx320213
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx339646
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx004798
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx010360-100ul 100 ul
EUR 493.2

Angiotensinogen (AGT) Antibody
20-abx301357
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiotensinogen Antibody / AGT
R30727 100ug
EUR 419

anti- Angiotensinogen antibody
FNab00393 100µg
EUR 658.5
Description: Antibody raised against Angiotensinogen

anti- Angiotensinogen antibody
FNab00394 100µg
EUR 606.3
Description: Antibody raised against Angiotensinogen

anti- Angiotensinogen antibody
FNab00395 100µg
EUR 606.3
Description: Antibody raised against Angiotensinogen

Rat angiotensinogen ELISA kit
55R-2262 1 kit
EUR 1647.6
Description: Rat angiotensinogen ELISA kit for use in research

Rat Angiotensinogen ELISA kit
E02A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen Antibody
11013-05011 150 ug
EUR 260.4

Eukaryotic Angiotensinogen (AGT)
4-EPA797Mu61
  • EUR 559.75
  • EUR 273.60
  • EUR 1769.09
  • EUR 669.70
  • EUR 1219.39
  • EUR 450.00
  • EUR 4242.72
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiotensinogen expressed in: 293F cell

Eukaryotic Angiotensinogen (AGT)
4-EPA797Ra61
  • EUR 566.21
  • EUR 274.80
  • EUR 1793.28
  • EUR 677.76
  • EUR 1235.52
  • EUR 454.80
  • EUR 4303.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Angiotensinogen expressed in: 293F cell

Goat Angiotensinogen ELISA kit
E06A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensinogen ELISA kit
E06A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensinogen ELISA kit
E06A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Acetyl Angiotensinogen (1-14), porcine
A1034-10 10 mg
EUR 164.4
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Acetyl Angiotensinogen (1-14), porcine
A1034-25 25 mg
EUR 205.2
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Acetyl Angiotensinogen (1-14), porcine
A1034-5 5 mg
EUR 122.4
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Rat Angiotensinogen (AGT) Protein
20-abx065353
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Angiotensinogen (AGT) Protein
20-abx651468
  • EUR 794.40
  • EUR 326.40
  • EUR 2414.40
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen ELISA kit
E03A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensinogen ELISA kit
E03A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensinogen ELISA kit
E03A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Angiotensinogen (AGT) Antibody (HRP)
20-abx306453
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monkey Angiotensinogen ELISA kit
E09A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensinogen ELISA kit
E09A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensinogen ELISA kit
E09A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen (AGT) CLIA Kit
abx195130-96tests 96 tests
EUR 990

Rat Angiotensinogen (AGT) CLIA Kit
20-abx492048
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Angiotensinogen (AGT) Antibody Pair
20-abx370425
  • EUR 1914.00
  • EUR 1228.80
  • 10 × 96 tests
  • 5 × 96 tests

Angiotensinogen (AGT) Antibody Pair
20-abx370604
  • EUR 2047.20
  • EUR 1312.80
  • 10 × 96 tests
  • 5 × 96 tests

Human Angiotensinogen (AGT) Protein
20-abx065351
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen (AGT) Protein
20-abx065352
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Angiotensinogen (AGT) Protein
20-abx065354
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen (AGT) Protein
20-abx651467
  • EUR 777.60
  • EUR 326.40
  • EUR 2380.80
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx273972
  • EUR 543.60
  • EUR 292.80
  • EUR 1579.20
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx274115
  • EUR 560.40
  • EUR 292.80
  • EUR 1663.20
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx306454
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Angiotensinogen (AGT) ELISA Kit
abx256349-96tests 96 tests
EUR 801.6

Rat Angiotensinogen (AGT) ELISA Kit
20-abx155199
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Angiotensinogen (AGT) ELISA Kit
abx573648-96tests 96 tests
EUR 858

Cow Angiotensinogen (AGT) ELISA Kit
abx514023-96tests 96 tests
EUR 1093.2

Pig Angiotensinogen (AGT) ELISA Kit
abx355132-96tests 96 tests
EUR 990

Rat angiotensinogen,aGT ELISA Kit
CN-01790R1 96T
EUR 536.4

Rat angiotensinogen,aGT ELISA Kit
CN-01790R2 48T
EUR 355.2

Rat Angiotensinogen (AGT) ELISA Kit
DLR-AGT-Ra-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Angiotensinogen (AGT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
DLR-AGT-Ra-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rat Angiotensinogen (AGT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat angiotensinogen (aGT) ELISA Kit
CSB-E08565r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat angiotensinogen (aGT) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat angiotensinogen (aGT) ELISA Kit
1-CSB-E08565r
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat angiotensinogen (aGT) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Agt(Angiotensinogen) ELISA Kit
ER0371 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.938 ng/ml

Rat Agt/ Angiotensinogen ELISA Kit
E0038Ra 1 Kit
EUR 685.2

Rat angiotensinogen(aGT)ELISA Kit
GA-E0665RT-48T 48T
EUR 447.6

Rat angiotensinogen(aGT)ELISA Kit
GA-E0665RT-96T 96T
EUR 730.8

Rat Angiotensinogen (AGT) ELISA Kit
RD-AGT-Ra-48Tests 48 Tests
EUR 540

Rat Angiotensinogen (AGT) ELISA Kit
RD-AGT-Ra-96Tests 96 Tests
EUR 746.4

Rat Angiotensinogen (AGT) ELISA Kit
RDR-AGT-Ra-48Tests 48 Tests
EUR 564

Rat Angiotensinogen (AGT) ELISA Kit
RDR-AGT-Ra-96Tests 96 Tests
EUR 781.2

Rat Angiotensinogen ELISA Kit (AGT)
RK03477 96 Tests
EUR 625.2

Rat angiotensinogen(aGT)ELISA Kit
QY-E10987 96T
EUR 433.2

Rat Angiotensinogen (AGT) ELISA Kit
SEA797Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Angiotensinogen (AGT) in serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
SEA797Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Angiotensinogen (AGT) in serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
SEA797Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Angiotensinogen (AGT) in serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
SEA797Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Angiotensinogen (AGT) in serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
4-SEA797Ra
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Angiotensinogen (AGT) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Angiotensinogen (AGT) ELISA Kit
RD-AGT-Ra-48T 48T
EUR 385
Description: serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
RD-AGT-Ra-96T 96T
EUR 550
Description: serum, plasma, tissue homogenates and other biological fluids.

Rat angiotensinogen,aGT ELISA Kit
YLA0162RA-48T 48T
EUR 465

Rat angiotensinogen,aGT ELISA Kit
YLA0162RA-96T 96T
EUR 600

Rat Angiotensinogen (AGT) ELISA Kit
RDR-AGT-Ra-48T 48T
EUR 404.25
Description: serum, plasma, tissue homogenates and other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
RDR-AGT-Ra-96T 96T
EUR 577.5
Description: serum, plasma, tissue homogenates and other biological fluids.

Human Angiotensinogen (AGT) CLIA Kit
20-abx190340
  • EUR 9493.20
  • EUR 5058.00
  • EUR 1167.60
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Angiotensinogen (AGT) CLIA Kit
20-abx190577
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Angiotensinogen (AGT) CLIA Kit
abx195128-96tests 96 tests
EUR 990

Mouse Angiotensinogen (AGT) CLIA Kit
abx195129-96tests 96 tests
EUR 990

Human Angiotensinogen (AGT)CLIA Kit
SCA797Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Human Angiotensinogen (AGT)CLIA Kit
SCA797Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Human Angiotensinogen (AGT)CLIA Kit
SCA797Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Human Angiotensinogen (AGT)CLIA Kit
SCA797Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Human Angiotensinogen (AGT) CLIA Kit
4-SCA797Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Angiotensinogen (AGT)Serum, plasma and other biological fluids

Mouse Angiotensinogen (AGT)CLIA Kit
SCA797Mu-10x96wellstestplate 10x96-wells test plate
EUR 6965.86
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Mouse Angiotensinogen (AGT)CLIA Kit
SCA797Mu-1x48wellstestplate 1x48-wells test plate
EUR 678.84
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Mouse Angiotensinogen (AGT)CLIA Kit
SCA797Mu-1x96wellstestplate 1x96-wells test plate
EUR 918.34
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Mouse Angiotensinogen (AGT)CLIA Kit
SCA797Mu-5x96wellstestplate 5x96-wells test plate
EUR 3772.51
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Angiotensinogen (AGT) in serum, plasma and other biological fluids.

Mouse Angiotensinogen (AGT) CLIA Kit
4-SCA797Mu
  • EUR 7026.00
  • EUR 3772.80
  • EUR 919.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Angiotensinogen (AGT)Serum, plasma and other biological fluids

Angiotensinogen Conjugated Antibody
C49159 100ul
EUR 476.4

Angiotensinogen (AGT) Antibody (Biotin)
20-abx272741
  • EUR 510.00
  • EUR 276.00
  • EUR 1462.80
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (Biotin)
20-abx273211
  • EUR 543.60
  • EUR 292.80
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (Biotin)
20-abx306455
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Angiotensinogen (AGT) ELISA Kit
abx253518-96tests 96 tests
EUR 801.6

Mouse Angiotensinogen (AGT) ELISA Kit
abx254811-96tests 96 tests
EUR 801.6

Human Angiotensinogen (AGT) ELISA Kit
20-abx150656
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human angiotensinogen,aGT ELISA Kit
201-12-1227 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Sheep Angiotensinogen (AGT) ELISA Kit
abx355368-96tests 96 tests
EUR 1111.2

Mouse Angiotensinogen (AGT) ELISA Kit
abx573245-96tests 96 tests
EUR 858

Human Angiotensinogen (AGT) ELISA Kit
abx573778-96tests 96 tests
EUR 801.6

Mouse angiotensinogen,aGT ELISA Kit
CN-02669M1 96T
EUR 560.4

Mouse angiotensinogen,aGT ELISA Kit
CN-02669M2 48T
EUR 379.2

Human angiotensinogen,aGT ELISA Kit
CN-03909H1 96T
EUR 542.4

Human angiotensinogen,aGT ELISA Kit
CN-03909H2 48T
EUR 362.4

Paw irritation, bone quantity (BV), and paw quantity (PV) had been assessed. Histologically, the entrance paws had been assessed for joint irritation, cartilage injury, and pre/osteoclast-like cells and the lumbar spinal wire and the periaqueductal grey (PAG) area of the mind for glial reactivity. A average CAIA dose induced (1) considerably larger native paw irritation, inflammatory cell infiltration, and PV; (2) considerably extra osteoclast-like cells on the bone floor and inside the surrounding comfortable tissue; and (3) considerably larger glial reactivity inside the PAG in contrast with the delicate CAIA mannequin. These findings assist the use of a average CAIA mannequin (increased dose of monoclonal antibodies with low-dose lipopolysaccharide) to induce extra constant histopathological options, with out extreme joint destruction.

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