Here, we evaluated the therapeutic potential of antibodies (Abs) focusing on cholinergic receptor nicotinic beta 2 subunit (CHRNB2) in gastric cancer. To examine the results of these Abs on malignant phenotypes in vitro and in mouse xenograft fashions, we generated gene knockouts by way of genome enhancing, carried out RNA interference-mediated knockdown of gene expression, and ectopically expressed CHRNB2 in gastric cancer cells. The results of anti-CHRNB2 Abs on the proliferation of cancer cells had been evaluated each in vitro and in vivo. We decided the results of Chrnb2 deficiency on mice and the medical significance of CHRNB2 expression in gastric cancer medical specimens.
Knockdown of CHRNB2 attenuated gastric cancer cell proliferation, whereas compelled overexpression of CHRNB2 elevated cell proliferation. Knockout of CHRNB2 considerably influenced cell survival and capabilities related with metastasis. The results of polyclonal Abs focusing on the C- and N-termini of CHRNB2 guided the improvement of anti-CHRNB2 monoclonal Abs that inhibited the development of gastric cancer cells in vitro and in vivo. Pathway evaluation revealed that CHRNB2 interfered with signaling by way of the PI3K-AKT and JAK-STAT pathways. Chrnb2-deficient mice exhibited regular replica, organ capabilities, and motor capabilities. CHRNB2 regulates a number of oncological phenotypes related with metastasis, and blockade of CHRNB2 expression utilizing particular Abs exhibits promise for controlling metastasis in gastric cancer.
About 25% of sufferers with IgA nephropathy (IgAN) progress to stage 5 persistent kidney illness (CKD) after years of evolution. Various instruments have been developed in recent times designed to foretell which of the sufferers will had poorer outcomes. The worth of circulating galactosyl-deficient IgA1 (Gd-IgA1) has been associated to a worse evolution of IgAN in a number of research. There are additionally some publications that relate greater APRIL values with a worse evolution. Recently, a new technique has been developed that enables measuring the worth of circulating Gd-IgA1 in a less complicated manner than these beforehand obtainable. The goal of this research is to investigate the affect of circulating Gd-IgA1, measured by this technique, on the development of IgAN.
Monoclonal Antibody Targeting the CD154 Cleavage Site Inhibits CD40-Dependent and -Independent Cleavage of CD154 from the Cell Surface
In addition to the membrane-bound molecule, soluble CD154 (sCD154) can also be detected at excessive ranges in the medium of activated T cells and platelets and in the serum of sufferers affected by completely different inflammatory ailments. This sCD154 is the consequence of cleavage of the full-length molecule between the glutamic acid residue at place 112 (E112) and methionine at place 113 (M113) and will be derived from the intracellular milieu and from cleavage of cell floor molecules. We have just lately reported that substitution of each E112 and M113 by alanine inhibits intracellular and CD40-induced membrane cleavage of CD154 and procures to CD154 an elevated organic operate as in contrast with cleavable CD154.

Thus, on this research, and in the intention of growing instruments inhibiting cleavage of CD154 from the cell floor, we generated a panel of anti-human CD154 mAbs. One of the derived mAbs that didn’t alter the binding of sCD154 to CD40, named on this research Clone eight mAb, completely misplaced its binding exercise in opposition to cells expressing CD154 mutated at its E112 and M113 residues. Treatment with Clone eight mAb was proven to fully abolish CD40-dependent and -independent cleavage of CD154 from the cell floor. Our research is highlighting the improvement and characterization of an modern therapeutic device succesful of inhibiting the launch/cleavage of CD154 from cells and thus sustaining its availability on the cell floor and the excessive in all probability of growing its efficiency as an activator of CD40-induced responses.
In this quasi-experimental pre-/postimplementation research, we estimated the effectiveness of MAb remedy inside 7 days of symptom onset in high-risk ambulatory adults with COVID-19. The main consequence was a composite of emergency division visits or hospitalizations inside 14 days of optimistic check. Secondary outcomes included adversarial occasions and 14-day mortality. The common remedy impact in the handled for MAb remedy was estimated utilizing inverse chance of remedy weighting and the affect of MAb implementation utilizing propensity-weighted interrupted time sequence evaluation.
Electrostatic Spray Drying for Monoclonal Antibody Formulation
This research explored the feasibility of electrostatic spray drying for producing a monoclonal antibody (mAb) powder formulation at decrease drying temperatures than typical spray drying and its impact on protein stability. A mAb formulation was dried by both typical spray drying or electrostatic spray drying with cost (ESD). The protein powders had been then characterised utilizing solid-state Fourier remodel infrared spectroscopy (ssFTIR), differential scanning calorimetry (DSC), dimension exclusion chromatography (SEC), and solid-state hydrogen/deuterium alternate with mass spectrometry (ssHDX-MS).
Particle characterizations reminiscent of BET floor space, particle dimension distribution, and particle morphology had been additionally carried out. Conventional spray drying of the mAb formulation at the inlet temperature of 70°C didn’t generate dry powders as a consequence of poor drying effectivity; electrostatic spray drying at the similar temperature at 5kV enabled the formation of powder formulation with passable moisture contents. Deconvoluted peak areas of deuterated samples from the ssHDX-MS research confirmed a good correlation with the loss of the monomeric peak space measured by dimension exclusion chromatography in the 90-day accelerated stability research carried out at 40°C.
DyLight®594 Conjugated Goat Anti-mouse IgG (H+L) |
BA1141-0.5 |
BosterBio |
0.5ml |
EUR 242.4 |
DyLight®594 Conjugated Goat Anti-mouse IgG (H+L) |
BA1141-1 |
BosterBio |
1ml |
EUR 400.8 |
Goat anti Mouse IgG (H + L) (Agarose Conjugated) |
43R-IG044AS |
Fitzgerald |
20 mg |
EUR 585.6 |
Description: Goat anti Mouse IgG (H + L) secondary antibody (Agarose Conjugated) |
DyLight®594 Conjugated Goat Anti-rabbit IgG (H+L) |
BA1142-0.5 |
BosterBio |
0.5ml |
EUR 242.4 |
DyLight®594 Conjugated Goat Anti-rabbit IgG (H+L) |
BA1142-1 |
BosterBio |
1ml |
EUR 400.8 |
Donkey anti Rat IgG (H + L) (Alexa Fluor 594) |
43R-ID022AF |
Fitzgerald |
500 ug |
EUR 436.8 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
Donkey anti Rat IgG (H + L) (Alexa Fluor 594) |
43R-ID047AF |
Fitzgerald |
500 ug |
EUR 554.4 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
XFD594 goat anti-mouse IgG (H+L) *Cross Adsorbed, XFD594 Same Structure to Alexa Fluor™ 594* |
16388 |
AAT Bioquest |
1 mg |
EUR 166 |
Goat anti-Mouse IgG(H+L), PE Conjugated |
E16SPP101-020 |
EnoGene |
20Tests |
EUR 286.8 |
Goat anti-Mouse IgG(H+L), PE Conjugated |
E16SPP101-050 |
EnoGene |
50Tests |
EUR 286.8 |
Goat anti-Mouse IgG(H+L), PE Conjugated |
E16SPP101-100U |
EnoGene |
100ug |
EUR 286.8 |
Goat anti-Mouse IgG(H+L), PE Conjugated |
E16SPP101-500U |
EnoGene |
500ug |
EUR 411.6 |
Annexin V, XFD594 conjugate *XFD594 Same Structure to Alexa Fluor™ 594* |
20096 |
AAT Bioquest |
100 tests |
EUR 222 |
XFD594-streptavidin conjugate *XFD594 Same Structure to Alexa Fluor™ 594* |
16892 |
AAT Bioquest |
1 mg |
EUR 166 |
Goat anti-Mouse IgG(H+L), FITC Conjugated |
E16SPF101-050 |
EnoGene |
50Tests |
EUR 286.8 |
Goat anti-Mouse IgG(H+L), FITC Conjugated |
E16SPF101-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti-Mouse IgG(H+L), FITC Conjugated |
E16SPF101-100U |
EnoGene |
100μg |
EUR 286.8 |
Goat anti-Mouse IgG(H+L), FITC Conjugated |
E16SPF101-500U |
EnoGene |
500μg |
EUR 411.6 |
Goat anti-Mouse IgG(H+L) ,HRPO Conjugated |
E16SPH101-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Mouse IgG(H+L) ,HRPO Conjugated |
E16SPH101-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Mouse IgG(H+L) ,HRPO Conjugated |
E16SPH101-500 |
EnoGene |
500μl |
EUR 411.6 |
Goat Anti-Mouse IgG (H+L) FITC -conjugated |
S0007 |
Affbiotech |
200ul |
EUR 540 |
Mouse anti Goat IgG heavy chain-HRP Conjugated Antibody |
C48068 |
SAB |
100ul |
EUR 476.4 |
Goat anti-Mouse IgG(H+L), Biotin Conjugated |
E16SPB101-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti-Mouse IgG(H+L), Biotin Conjugated |
E16SPB101-1000 |
EnoGene |
1000Tests |
EUR 294 |
Goat anti-Mouse IgG(H+L), Biotin Conjugated |
E16SPB101-500 |
EnoGene |
500Tests |
EUR 200.4 |
Mouse anti goat IgG lighty chain-HRP Conjugated Antibody |
C48078 |
SAB |
100ul |
EUR 476.4 |
XFD594 goat anti-rabbit IgG (H+L) *Cross Adsorbed, XFD594 Same Structure to Alexa Fluor™ 594* |
16404 |
AAT Bioquest |
1 mg |
EUR 166 |
Streptavidin-Alexa594 (Alexas fluor 594) conjugate |
SV-A594-100 |
Alpha Diagnostics |
100 tests |
EUR 270 |
Goat anti Human IgG (Fc) (Agarose Conjugated) |
43R-IG016AS |
Fitzgerald |
2 ml |
EUR 457.2 |
Description: Goat anti Human IgG secondary antibody (Fc) (Agarose Conjugated) |
Goat Anti-Mouse IgG Secondary Antibody PE Conjugated |
L30317 |
SAB |
1.0 ml |
EUR 229.2 |
Goat Anti-Mouse IgG Secondary Antibody AP Conjugated |
L3033 |
SAB |
1.0 ml |
EUR 142.8 |
Goat Anti-Mouse IgG Secondary Antibody Cy3 Conjugated |
L30311 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Mouse IgG Secondary Antibody APC Conjugated |
L30316 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Mouse IgG Secondary Antibody HRP Conjugated |
L3032 |
SAB |
1.0 ml |
EUR 134.4 |
Goat anti-Mouse IgG SecondaryAntibody (peroxidase conjugated) |
E0L3032-1 |
EnoGene |
500ul |
EUR 153.6 |
Goat Anti-Mouse IgG Secondary Antibody FITC Conjugated |
L30313 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Mouse IgG Secondary Antibody AMCA Conjugated |
L3035 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Mouse IgG Secondary Antibody AF790 Conjugated |
L30310 |
SAB |
0.5 ml |
EUR 151.2 |
Goat Anti-Mouse IgG Secondary Antibody PerCP Conjugated |
L30318 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Mouse IgG Secondary Antibody AF488 Conjugated |
L3036 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Mouse IgG Secondary Antibody AF594 Conjugated |
L3037 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Mouse IgG Secondary Antibody AF647 Conjugated |
L3038 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Mouse IgG Secondary Antibody AF680 Conjugated |
L3039 |
SAB |
0.5 ml |
EUR 151.2 |
Goat Anti-Mouse IgG Secondary Antibody Biotin Conjugated |
L3034 |
SAB |
1.0 ml |
EUR 124.8 |
Goat anti-Rabbit IgG(H+L), PE Conjugated |
E16SPP102-050 |
EnoGene |
50Tests |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), PE Conjugated |
E16SPP102-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti-Rabbit IgG(H+L), PE Conjugated |
E16SPP102-100U |
EnoGene |
100ug |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), PE Conjugated |
E16SPP102-500U |
EnoGene |
500ug |
EUR 411.6 |
DyLight®488 Conjugated Goat Anti-mouse IgG (H+L) |
BA1126-0.5 |
BosterBio |
0.5ml |
EUR 242.4 |
DyLight®488 Conjugated Goat Anti-mouse IgG (H+L) |
BA1126-1 |
BosterBio |
1ml |
EUR 400.8 |
Goat anti- Human IgG(H+L) ,Biotin Conjugated |
E16SPB103-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti- Human IgG(H+L) ,Biotin Conjugated |
E16SPB103-1000 |
EnoGene |
1000Tests |
EUR 294 |
Goat anti- Human IgG(H+L) ,Biotin Conjugated |
E16SPB103-500 |
EnoGene |
500Tests |
EUR 200.4 |
Goat anti-Human IgG(H+L) ,HRPO Conjugated |
E16SPH103-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Human IgG(H+L) ,HRPO Conjugated |
E16SPH103-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Human IgG(H+L) ,HRPO Conjugated |
E16SPH103-500 |
EnoGene |
500μl |
EUR 411.6 |
Goat anti- Rabbit IgG(H+L), Biotin Conjugated |
E16SPB102-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti- Rabbit IgG(H+L), Biotin Conjugated |
E16SPB102-1000 |
EnoGene |
1000Tests |
EUR 294 |
Goat anti- Rabbit IgG(H+L), Biotin Conjugated |
E16SPB102-500 |
EnoGene |
500Tests |
EUR 200.4 |
Goat anti-Rabbit IgG(H+L), FITC Conjugated |
E16SPF102-050 |
EnoGene |
50Tests |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), FITC Conjugated |
E16SPF102-100 |
EnoGene |
100Tests |
EUR 411.6 |
Goat anti-Rabbit IgG(H+L), FITC Conjugated |
E16SPF102-100U |
EnoGene |
100μg |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), FITC Conjugated |
E16SPF102-500U |
EnoGene |
500μg |
EUR 411.6 |
Goat anti-Rabbit IgG(H+L), HRPO Conjugated |
E16SPH102-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), HRPO Conjugated |
E16SPH102-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Rabbit IgG(H+L), HRPO Conjugated |
E16SPH102-500 |
EnoGene |
500μl |
EUR 411.6 |
Goat anti Bovine IgG (H + L) (Agarose Conjugated) |
43R-IG043AS |
Fitzgerald |
20 mg |
EUR 478.8 |
Description: Goat anti Bovine IgG (H + L) secondary antibody (Agarose Conjugated) |
Goat anti Rabbit IgG (H + L) (Agarose Conjugated) |
43R-IG045AS |
Fitzgerald |
20 mg |
EUR 570 |
Description: Goat anti Rabbit IgG (H + L) secondary antibody (Agarose Conjugated) |
XFD594 goat anti-mouse IgG (H+L) *Cross Adsorbed, XFD594 Same Structure to Alexa Fluorâ„¢ 594* |
16388-1mg |
AAT Bioquest |
1 mg |
EUR 166 |
|
Description: XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). |
Goat anti-Human IgG(H+L) ,Cross absorbed against mouse immunoglobulinsHRPO ConjugatedHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1031-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Human IgG(H+L) ,Cross absorbed against mouse immunoglobulinsHRPO ConjugatedHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1031-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Human IgG(H+L) ,Cross absorbed against mouse immunoglobulinsHRPO ConjugatedHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1031-500 |
EnoGene |
500μl |
EUR 411.6 |
Rabbit anti Goat IgG (H + L) (Agarose Conjugated) |
43R-IR004AS |
Fitzgerald |
20 mg |
EUR 649.2 |
Description: Rabbit anti Goat IgG (H + L) secondary antibody (Agarose Conjugated) |
Goat Anti-Human IgG Secondary Antibody PE Conjugated |
L30217 |
SAB |
1.0 ml |
EUR 229.2 |
Goat Anti-Human IgG Secondary Antibody AP Conjugated |
L3023 |
SAB |
1.0 ml |
EUR 142.8 |
Goat Anti-Mouse IgG Secondary Antibody Rhodamine (RRX) Conjugated |
L30315 |
SAB |
1.0 ml |
EUR 116.4 |
Cy3 Conjugated Goat Anti-Mouse IgG (H+L) secondary antibody |
BA1031 |
BosterBio |
0.5ml |
EUR 218.4 |
HRP Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1050-0.5 |
BosterBio |
0.5ml |
EUR 175.2 |
HRP Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1050-1 |
BosterBio |
1ml |
EUR 279.6 |
Goat Anti-Mouse IgG Secondary Antibody Rhodamine (TRITC) Conjugated |
L30314 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Rabbit IgG Secondary Antibody PE Conjugated |
L30117 |
SAB |
1.0 ml |
EUR 229.2 |
Goat Anti-Human IgG Secondary Antibody Cy3 Conjugated |
L30211 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Human IgG Secondary Antibody APC Conjugated |
L30216 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Human IgG Secondary Antibody HRP Conjugated |
L3022 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Rabbit IgG Secondary Antibody AP Conjugated |
L3073 |
SAB |
1.0 ml |
EUR 142.8 |
FITC Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1101-0.5 |
BosterBio |
0.5mL |
EUR 157.2 |
FITC Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1101-1 |
BosterBio |
1mL |
EUR 242.4 |
Goat Anti-Rabbit IgG Secondary Antibody Cy3 Conjugated |
L30111 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Rabbit IgG Secondary Antibody APC Conjugated |
L30116 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Rabbit IgG Secondary Antibody HRP Conjugated |
L3012 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Human IgG Secondary Antibody FITC Conjugated |
L30213 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Human IgG Secondary Antibody AMCA Conjugated |
L3025 |
SAB |
1.0 ml |
EUR 116.4 |
TRITC Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1089-0.5 |
BosterBio |
0.5ml |
EUR 224.4 |
TRITC Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1089-1 |
BosterBio |
1ml |
EUR 400.8 |
Goat anti-Rabbit IgG(H+L) ,Cross absorbed against human and mouse immunoglobulinsHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1022-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L) ,Cross absorbed against human and mouse immunoglobulinsHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1022-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Rabbit IgG(H+L) ,Cross absorbed against human and mouse immunoglobulinsHRPO ConjugatedHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1022-500 |
EnoGene |
500μl |
EUR 411.6 |
Goat Anti-Rabbit IgG Secondary Antibody FITC Conjugated |
L30113 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Human IgG Secondary Antibody PerCP Conjugated |
L30218 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Human IgG Secondary Antibody AF488 Conjugated |
L3026 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Human IgG Secondary Antibody AF594 Conjugated |
L3027 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Human IgG Secondary Antibody AF647 Conjugated |
L3028 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Rabbit IgG Secondary Antibody AMCA Conjugated |
L3065 |
SAB |
1.0 ml |
EUR 116.4 |
Biotin Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1001-0.5 |
BosterBio |
0.5ml |
EUR 115.2 |
Biotin Conjugated Goat Anti-mouse IgG (H+L) secondary antibody |
BA1001-1 |
BosterBio |
1ml |
EUR 157.2 |
Goat Anti-Rabbit IgG Secondary Antibody PerCP Conjugated |
L30118 |
SAB |
0.5 ml |
EUR 229.2 |
Goat Anti-Rabbit IgG Secondary Antibody AF488 Conjugated |
L3016 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Rabbit IgG Secondary Antibody AF594 Conjugated |
L3017 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Rabbit IgG Secondary Antibody AF647 Conjugated |
L3018 |
SAB |
1.0 ml |
EUR 134.4 |
Goat Anti-Human IgG Secondary Antibody Biotin Conjugated |
L3024 |
SAB |
1.0 ml |
EUR 124.8 |
Goat Anti-Rabbit IgG Secondary Antibody AF680 Conjugated |
L3049 |
SAB |
0.5 ml |
EUR 151.2 |
Goat Anti-Rabbit IgG Secondary Antibody AF790 Conjugated |
L30510 |
SAB |
0.5 ml |
EUR 151.2 |
Goat Anti-Mouse IgG (Fc) colloidal gold conjugated (40 nm, OD10) |
CG-40151 |
Alpha Diagnostics |
500 ul |
EUR 270 |
Goat Anti-Rabbit IgG Secondary Antibody Biotin Conjugated |
L3014 |
SAB |
1.0 ml |
EUR 124.8 |
Goat Anti-Mouse IgG (Fc) IgG-FITC Conjugate |
40151-FITC |
Alpha Diagnostics |
1 ml |
EUR 270 |
XFD350 goat anti-mouse IgG (H+L) *Cross Adsorbed, XFD350 Same Structure to Alexa Fluor™ 350* |
16380 |
AAT Bioquest |
1 mg |
EUR 166 |
XFD488 goat anti-mouse IgG (H+L) *Cross Adsorbed, XFD488 Same Structure to Alexa Fluor™ 488* |
16383 |
AAT Bioquest |
1 mg |
EUR 166 |
DyLight®488 Conjugated Goat Anti-rabbit IgG (H+L) |
BA1127-0.5 |
BosterBio |
0.5ml |
EUR 242.4 |
DyLight®488 Conjugated Goat Anti-rabbit IgG (H+L) |
BA1127-1 |
BosterBio |
1ml |
EUR 400.8 |
Goat anti-Rabbit IgG SecondaryAntibody (peroxidase conjugated) |
E0L3012-1 |
EnoGene |
500ul |
EUR 153.6 |
Goat anti-Rabbit IgG SecondaryAntibody (peroxidase conjugated) |
E0L3012-2 |
EnoGene |
1000ul |
EUR 216 |
Annexin V, XFD594 conjugate *XFD594 Same Structure to Alexa Fluorâ„¢ 594* |
20096-100tests |
AAT Bioquest |
100 tests |
EUR 222 |
|
Description: XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). |
Goat Anti-Mouse IgG (Fc) IgG-Biotin Conjugate |
40151-BT |
Alpha Diagnostics |
1 ml |
EUR 270 |
XFD594-streptavidin conjugate *XFD594 Same Structure to Alexa Fluorâ„¢ 594* |
16892-1mg |
AAT Bioquest |
1 mg |
EUR 166 |
|
Description: XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). |
Goat IgG heavy chain Conjugated Antibody |
C48065 |
SAB |
100ul |
EUR 476.4 |
XFD594 goat anti-rabbit IgG (H+L) *Cross Adsorbed, XFD594 Same Structure to Alexa Fluorâ„¢ 594* |
16404-1mg |
AAT Bioquest |
1 mg |
EUR 166 |
|
Description: XFD594 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 594 (Alexa Fluor® is the trademark of ThermoFisher). |
Goat Anti-mouse IgG (H+L) colloidal gold conjugated (40 nm, OD10) |
CG-40320 |
Alpha Diagnostics |
500 ul |
EUR 270 |
Annexin V, XFD350 conjugate *XFD350 Same Structure to Alexa Fluor™ 350* |
20090 |
AAT Bioquest |
100 tests |
EUR 222 |
Annexin V, XFD488 conjugate *XFD488 Same Structure to Alexa Fluor™ 488* |
20092 |
AAT Bioquest |
100 tests |
EUR 222 |
Goat Anti-Human IgG Secondary Antibody Rhodamine (RRX) Conjugated |
L30215 |
SAB |
1.0 ml |
EUR 116.4 |
Cy3 Conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody |
BA1032 |
BosterBio |
0.5ml |
EUR 218.4 |
HRP Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1054-0.5 |
BosterBio |
0.5ml |
EUR 175.2 |
HRP Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1054-1 |
BosterBio |
1ml |
EUR 279.6 |
Goat Anti-Rabbit IgG Secondary Antibody Rhodamine (RRX) Conjugated |
L30115 |
SAB |
1.0 ml |
EUR 116.4 |
Goat Anti-Human IgG Secondary Antibody Rhodamine (TRITC) Conjugated |
L30214 |
SAB |
1.0 ml |
EUR 116.4 |
FITC Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1105-0.5 |
BosterBio |
0.5mL |
EUR 157.2 |
FITC Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1105-1 |
BosterBio |
1mL |
EUR 242.4 |
XFD350 goat anti-rabbit IgG (H+L) *Cross Adsorbed, XFD350 Same Structure to Alexa Fluor™ 350* |
16395 |
AAT Bioquest |
1 mg |
EUR 166 |
XFD488 goat anti-rabbit IgG (H+L) *Cross Adsorbed, XFD488 Same Structure to Alexa Fluor™ 488* |
16398 |
AAT Bioquest |
1 mg |
EUR 166 |
Goat Anti-Rat IgG (Fc) colloidal gold conjugated (40 nm, OD10) |
CG-50119 |
Alpha Diagnostics |
500 ul |
EUR 270 |
XFD350-streptavidin conjugate *XFD350 Same Structure to Alexa Fluor™ 350* |
16890 |
AAT Bioquest |
1 mg |
EUR 166 |
XFD488-streptavidin conjugate *XFD488 Same Structure to Alexa Fluor™ 488* |
16891 |
AAT Bioquest |
1 mg |
EUR 166 |
TRITC Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1090-0.5 |
BosterBio |
0.5ml |
EUR 224.4 |
TRITC Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1090-1 |
BosterBio |
1ml |
EUR 400.8 |
Goat Anti-Rabbit IgG Secondary Antibody Rhodamine (TRITC) Conjugated |
L30114 |
SAB |
1.0 ml |
EUR 116.4 |
Biotin Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1003-0.5 |
BosterBio |
0.5ml |
EUR 115.2 |
Biotin Conjugated Goat Anti-rabbit IgG (H+L) secondary antibody |
BA1003-1 |
BosterBio |
1ml |
EUR 157.2 |
Goat Anti-Human IgG (Fc) colloidal gold conjugated (40 nm, OD10) |
CG-10119 |
Alpha Diagnostics |
500 ul |
EUR 270 |
Goat anti-rabbit IgG (Fc) colloidal gold conjugated (40 nm, OD10) |
CG-20119 |
Alpha Diagnostics |
500 ul |
EUR 270 |
Goat Anti-Human IgG (Fc) IgG-HRP Conjugate |
10119-HP |
Alpha Diagnostics |
0.5 ml |
EUR 255.6 |
Goat anti-Mouse IgG(H+L) ,Cross absorbed against human and rat immunoglobulinsHRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1013-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Mouse IgG(H+L) ,Cross absorbed against human and rat immunoglobulinsHRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1013-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Mouse IgG(H+L) ,Cross absorbed against human and rat immunoglobulinsHRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1013-500 |
EnoGene |
500μl |
EUR 411.6 |
DiagPoly Goat Anti-mouse IgG (Fc) Conjugated Polystyrene Particles, 0.7-0.9 µm |
DNM-C019 |
Creative Diagnostics |
20 mL |
EUR 999.6 |
DiagPoly Goat Anti-mouse IgG (Fc) Conjugated Polystyrene Particles, 3.0-3.9 µm |
DNM-C024 |
Creative Diagnostics |
5 mL |
EUR 1062 |
DiagPoly Goat Anti-mouse IgG (Fc) Conjugated Polystyrene Particles, 6.0-8.0 µm |
DNM-C025 |
Creative Diagnostics |
5 mL |
EUR 1062 |
Goat anti-Rabbit IgG(H+L), Cross absorbed against human immunoglobulinsHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1021-100 |
EnoGene |
100μl |
EUR 286.8 |
Goat anti-Rabbit IgG(H+L), Cross absorbed against human immunoglobulinsHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1021-1000 |
EnoGene |
1000μl |
EUR 520.8 |
Goat anti-Rabbit IgG(H+L), Cross absorbed against human immunoglobulinsHRPO Conjugated HRPO Conjugated HRPO ConjugatedHRPO Conjugated |
E16SPH1021-500 |
EnoGene |
500μl |
EUR 411.6 |
Low-temperature (70°C inlet temperature) drying with an electrostatic cost (5kV) led to higher protein bodily stability as in contrast with the samples spray-dried at the excessive temperature (130°C inlet temperature) with out cost. This research exhibits that electrostatic spray drying can produce strong monoclonal antibody formulation at decrease inlet temperature than conventional spray drying with higher bodily stability.