The identification and management of monoclonal antibody (mAb) vital high quality attributes (CQAs) is a key element of high quality by design (QbD). In this work, fast peptide mapping and native intact cost variants evaluation have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis – mass spectrometry (CE-MS) platform. The ultrafast peptide mapping concurrently analyzed a number of CQAs, together with protein major construction, oxidation, deamidation, succinimide, C-terminal lysine (Lys) clipping, N-terminal cyclization, and glycosylation. The microfluidic CE-MS primarily based peptide mapping acquired outcomes comparable to standard however prolonged liquid chromatography – MS (LC-MS) primarily based method.
The native intact evaluation resolved mAb cost variants with a comparable decision as generally achieved using capillary isoelectric focusing (cIEF). Charge variants’ identities had been assigned primarily based on attribute mass shifts, information realized from peptide mapping, and adjustments in electrophoretic mobility. Major mAb glycoforms of every cost variants had been resolved and recognized within the deconvoluted mass spectra. Furthermore, a mannequin simulation was carried out to reconstruct intact deconvoluted mass spectra using peptide mapping outcomes.
The reconstructed and experimentally decided intact deconvoluted mass spectra had been extremely correlated, suggesting that our information collected on the peptide stage and intact stage had been constant and extremely comparable. Overall, the microfluidic CE-MS primarily based peptide mapping and native intact cost variants evaluation are high-throughput strategies which have nice potential to assist biopharmaceutical growth. Coronavirus illness 2019 (COVID-19) continues to emphasize the well being care system. Neutralizing monoclonal antibodies (mAbs) had been efficient in lowering COVID-19-related hospitalizations and emergency division (ED) visits of their respective medical trials.
Computational modeling of microfluidic information supplies high-throughput affinity estimates for monoclonal antibodies
Affinity measurement is a elementary step within the discovery of monoclonal antibodies (mAbs) and of antigens appropriate for vaccine growth. Innovative affinity assays are wanted as a result of low throughput and/or restricted dynamic vary of obtainable applied sciences. We mixed microfluidic expertise with quantum-mechanical scattering concept, so as to develop a high-throughput, broad-range methodology to measure affinity. Fluorescence depth profiles had been generated for out-of-equilibrium options of labelled mAbs and their antigen-binding fragments migrating alongside micro-columns with immobilized cognate antigen.
Affinity quantification was carried out by computational information evaluation primarily based on the Landau chance distribution. Experiments using a big selection of human or murine antibodies in opposition to bacterial or viral, protein or polysaccharide antigens, confirmed that every one the antibody-antigen seize profiles (n = 841) generated at completely different concentrations had been precisely described by the Landau distribution. A scale parameter W, proportional to the full-width-at-half-maximum of the seize profile, was proven to be unbiased of the antibody focus. Glycerol phosphate (GroP)-based teichoic acids (TAs) are antigenic cell-wall parts present in each enterococcus and staphylococcus species.
Their immunogenicity has been explored using each native and artificial buildings, however no particulars have but been reported on the structural foundation of their interplay with antibodies. This work represents the primary case research during which a monoclonal antibody, generated in opposition to an artificial TA, was developed and employed for molecular-level binding evaluation using TA microarrays, ELISA, SPR-analyses, and STD-NMR spectroscopy. However, these outcomes have but to be reproduced in a sensible setting following implementation of present US Food and Drug Administration (FDA) steering.
Method growth for the clearance research of the Pluronic F-68 nonionic surfactant used within the upstream means of monoclonal antibody manufacturing
Pluronic F-68 is a nonionic surfactant, which is usually used within the upstream means of biopharmaceutical manufacturing. However, the variety of analytical strategies developed for dedication of Pluronic F-68 within the in-process and drug substance samples of organic drug manufacturing course of is kind of low. The lack of chromophore teams on the molecule and the interference attributable to the excessive protein content material of the samples hamper evaluation. In this paper the event and qualification of a mixed-mode (MM) HPLC technique with charged aerosol detection is reported.
The technique allows the evaluation of samples with as much as 85 g/L protein focus. The vary of the tactic was set to 250-500 μg/mL, the place it was discovered to be correct (89-111 % restoration) and exact (0.8-3.2 % relative normal deviation). The excessive sensitivity of the tactic signifies that even decrease focus vary may be possible. The novel technique efficiently demonstrates Pluronic F-68 clearance throughout the downstream means of the monoclonal antibody manufacturing.
A novel and efficient method to generate germline-like monoclonal antibodies by integration of phage and mammalian cell show platforms
Phage show expertise permits for fast number of antibodies from the big repertoire of human antibody fragments displayed on phages. However, antibody fragments needs to be transformed to IgG for organic characterizations and affinity of antibodies obtained from phage show library is often not enough for environment friendly use in medical settings. Here, we describe a brand new method that mixes phage and mammalian cell show, enabling simultaneous affinity screening of full-length IgG antibodies. Using this technique, we efficiently obtained a novel germline-like anti-TIM-3 monoclonal antibody named m101, which was revealed to be a potent anti-TIM-Three therapeutic monoclonal antibody by way of in vitro and in vivo experiments, indicating its effectiveness and energy.
) Recombinant Angiotensinogen (AGT) |
|
4-RPA797Ra01 |
Cloud-Clone |
-
EUR 496.32
-
EUR 256.80
-
EUR 1531.20
-
EUR 590.40
-
EUR 1060.80
-
EUR 408.00
-
EUR 3648.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Angiotensinogen expressed in: E.coli |
 Recombinant Human Angiotensinogen Protein |
|
RP01021 |
Abclonal |
5 μg |
EUR 219.6 |
 Angiotensinogen antibody |
|
70R-12752 |
Fitzgerald |
100 ul |
EUR 548.4 |
|
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody |
Angiotensinogen antibody |
|
70R-13411 |
Fitzgerald |
100 ul |
EUR 548.4 |
|
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody |
 Angiotensinogen Antibody |
|
49159-100ul |
SAB |
100ul |
EUR 399.6 |
Angiotensinogen Antibody |
|
49159-50ul |
SAB |
50ul |
EUR 286.8 |
Angiotensinogen antibody |
|
10R-A130a |
Fitzgerald |
200 ul |
EUR 678 |
|
Description: Mouse monoclonal Angiotensinogen antibody |
Angiotensinogen antibody |
|
10R-A131a |
Fitzgerald |
200 ul |
EUR 548.4 |
|
Description: Mouse monoclonal Angiotensinogen antibody |
 Angiotensinogen Peptide |
|
20-abx265209 |
Abbexa |
-
EUR 678.00
-
EUR 1144.80
-
EUR 477.60
|
|
|
|
Angiotensinogen Peptide |
|
20-abx265535 |
Abbexa |
-
EUR 661.20
-
EUR 1111.20
-
EUR 477.60
|
|
|
|
Angiotensinogen Peptide |
|
20-abx266414 |
Abbexa |
-
EUR 627.60
-
EUR 1045.20
-
EUR 460.80
|
|
|
|
Angiotensinogen Peptide |
|
20-abx266467 |
Abbexa |
-
EUR 661.20
-
EUR 1111.20
-
EUR 477.60
|
|
|
|
 Human Angiotensinogen Antibody |
|
11013-05011 |
AssayPro |
150 ug |
EUR 260.4 |
 Angiotensinogen Rabbit mAb |
|
A11689-100ul |
Abclonal |
100 ul |
EUR 492 |
Angiotensinogen Rabbit mAb |
|
A11689-200ul |
Abclonal |
200 ul |
EUR 685.2 |
Angiotensinogen Rabbit mAb |
|
A11689-20ul |
Abclonal |
20 ul |
EUR 265.2 |
Angiotensinogen Rabbit mAb |
|
A11689-50ul |
Abclonal |
50 ul |
EUR 344.4 |
 Antibody) Angiotensinogen (AGT) Antibody |
|
20-abx171240 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101137 |
Abbexa |
-
EUR 477.60
-
EUR 159.60
-
EUR 1328.40
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101138 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101139 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101140 |
Abbexa |
-
EUR 393.60
-
EUR 978.00
-
EUR 510.00
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx004798 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx128540 |
Abbexa |
-
EUR 477.60
-
EUR 159.60
-
EUR 1328.40
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx110982 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
abx010360-100ul |
Abbexa |
100 ul |
EUR 493.2 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033720-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033720-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033721-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033721-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx320213 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx322250 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
abx230393-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx230394-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx230395-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241726 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241946 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241947 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx242324 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx301357 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx339646 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx211344 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx214416 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx175400 |
Abbexa |
|
|
|
|
) Human Angiotensinogen (AGT) |
|
1-CSB-EP001463HU1 |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Human Angiotensinogen(AGT),partial expressed in E.coli |
 Angiotensinogen Conjugated Antibody |
|
C49159 |
SAB |
100ul |
EUR 476.4 |
) Eukaryotic Angiotensinogen (AGT) |
|
4-EPA797Mu61 |
Cloud-Clone |
-
EUR 559.75
-
EUR 273.60
-
EUR 1769.09
-
EUR 669.70
-
EUR 1219.39
-
EUR 450.00
-
EUR 4242.72
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Angiotensinogen expressed in: 293F cell |
Eukaryotic Angiotensinogen (AGT) |
|
4-EPA797Ra61 |
Cloud-Clone |
-
EUR 566.21
-
EUR 274.80
-
EUR 1793.28
-
EUR 677.76
-
EUR 1235.52
-
EUR 454.80
-
EUR 4303.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Angiotensinogen expressed in: 293F cell |
 anti- Angiotensinogen antibody |
|
FNab00393 |
FN Test |
100µg |
EUR 658.5 |
|
|
|
Description: Antibody raised against Angiotensinogen |
anti- Angiotensinogen antibody |
|
FNab00394 |
FN Test |
100µg |
EUR 606.3 |
|
|
|
Description: Antibody raised against Angiotensinogen |
anti- Angiotensinogen antibody |
|
FNab00395 |
FN Test |
100µg |
EUR 606.3 |
|
|
|
Description: Antibody raised against Angiotensinogen |
 Rat angiotensinogen ELISA kit |
|
55R-2262 |
Fitzgerald |
1 kit |
EUR 1647.6 |
|
Description: Rat angiotensinogen ELISA kit for use in research |
 Anti-Angiotensinogen/AGT Antibody |
|
A02103-1 |
BosterBio |
100ug/vial |
EUR 400.8 |
, human) Angiotensinogen (1-14), human |
|
5-00697 |
CHI Scientific |
4 x 5mg |
Ask for price |
, Porcine) Angiotensinogen (1-14), Porcine |
|
5-00698 |
CHI Scientific |
4 x 5mg |
Ask for price |
 , Rat) Angiotensinogen (1-14) , Rat |
|
5-00699 |
CHI Scientific |
4 x 5mg |
Ask for price |
 Protein) Human Angiotensinogen (AGT) Protein |
|
20-abx065351 |
Abbexa |
-
EUR 895.20
-
EUR 360.00
-
EUR 2798.40
-
EUR 1062.00
-
EUR 627.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Mouse Angiotensinogen (AGT) Protein |
|
20-abx065352 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Rat Angiotensinogen (AGT) Protein |
|
20-abx065353 |
Abbexa |
-
EUR 693.60
-
EUR 309.60
-
EUR 2064.00
-
EUR 828.00
-
EUR 510.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Human Angiotensinogen (AGT) Protein |
|
20-abx065354 |
Abbexa |
-
EUR 895.20
-
EUR 360.00
-
EUR 2798.40
-
EUR 1062.00
-
EUR 627.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody Pair) Angiotensinogen (AGT) Antibody Pair |
|
20-abx370425 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
|
Angiotensinogen (AGT) Antibody Pair |
|
20-abx370604 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
|
 Antibody (FITC)) Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx273972 |
Abbexa |
-
EUR 543.60
-
EUR 292.80
-
EUR 1579.20
-
EUR 760.80
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx274115 |
Abbexa |
-
EUR 560.40
-
EUR 292.80
-
EUR 1663.20
-
EUR 777.60
-
EUR 427.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody (Biotin)) Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx272741 |
Abbexa |
-
EUR 510.00
-
EUR 276.00
-
EUR 1462.80
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx273211 |
Abbexa |
-
EUR 543.60
-
EUR 292.80
-
EUR 1545.60
-
EUR 744.00
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody (HRP)) Angiotensinogen (AGT) Antibody (HRP) |
|
20-abx306453 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx306454 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx306455 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Mouse Angiotensinogen (AGT) Protein |
|
20-abx651467 |
Abbexa |
-
EUR 777.60
-
EUR 326.40
-
EUR 2380.80
-
EUR 927.60
-
EUR 560.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Rat Angiotensinogen (AGT) Protein |
|
20-abx651468 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2414.40
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Rabbit Angiotensinogen ELISA kit |
|
E04A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensinogen ELISA kit |
|
E04A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensinogen ELISA kit |
|
E04A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Goat Angiotensinogen ELISA kit |
|
E06A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensinogen ELISA kit |
|
E06A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensinogen ELISA kit |
|
E06A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Dog Angiotensinogen ELISA kit |
|
E08A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensinogen ELISA kit |
|
E08A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensinogen ELISA kit |
|
E08A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse Angiotensinogen ELISA kit |
|
E03A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Angiotensinogen ELISA kit |
|
E03A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Angiotensinogen ELISA kit |
|
E03A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Monkey Angiotensinogen ELISA kit |
|
E09A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensinogen ELISA kit |
|
E09A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensinogen ELISA kit |
|
E09A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rat Angiotensinogen ELISA kit |
|
E02A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensinogen ELISA kit |
|
E02A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensinogen ELISA kit |
|
E02A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Human Angiotensinogen ELISA kit |
|
E01A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensinogen ELISA kit |
|
E01A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensinogen ELISA kit |
|
E01A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Pig Angiotensinogen ELISA kit |
|
E07A0497-192T |
BlueGene |
192 tests |
EUR 1524 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensinogen ELISA kit |
|
E07A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensinogen ELISA kit |
|
E07A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Anti-Angiotensinogen/AGT Antibody |
|
PA1643 |
BosterBio |
100ug/vial |
EUR 352.8 |
) Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His) |
|
CB56-10ug |
Novoprotein |
10ug |
EUR 242.4 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His) |
|
CB56-1mg |
Novoprotein |
1mg |
EUR 2983.2 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His) |
|
CB56-500ug |
Novoprotein |
500ug |
EUR 2106 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His) |
|
CB56-50ug |
Novoprotein |
50ug |
EUR 595.2 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
) Human Angiotensinogen Antibody (Biotin Conjugate) |
|
11013-05021 |
AssayPro |
150 ug |
EUR 331.2 |
, porcine) Acetyl Angiotensinogen (1-14), porcine |
|
A1034-10 |
ApexBio |
10 mg |
EUR 164.4 |
|
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5. |
Acetyl Angiotensinogen (1-14), porcine |
|
A1034-25 |
ApexBio |
25 mg |
EUR 205.2 |
|
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5. |
Acetyl Angiotensinogen (1-14), porcine |
|
A1034-5 |
ApexBio |
5 mg |
EUR 122.4 |
|
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5. |
, human) Ac-Angiotensinogen (1-14), human |
|
5-00549 |
CHI Scientific |
4 x 1mg |
Ask for price |
, porcine) Ac-Angiotensinogen (1-14), porcine |
|
5-00550 |
CHI Scientific |
4 x 1mg |
Ask for price |
 ELISA Kit) Human Angiotensinogen (AGT) ELISA Kit |
|
20-abx150656 |
Abbexa |
-
EUR 7970.40
-
EUR 4250.40
-
EUR 990.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
 ELISA Kit) Rat Angiotensinogen (AGT) ELISA Kit |
|
20-abx155199 |
Abbexa |
-
EUR 8684.40
-
EUR 4626.00
-
EUR 1074.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
 ELISA Kit) Mouse Angiotensinogen (AGT) ELISA Kit |
|
20-abx153638 |
Abbexa |
-
EUR 7970.40
-
EUR 4250.40
-
EUR 990.00
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
Human Angiotensinogen (AGT) ELISA Kit |
|
abx253518-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
|
Mouse Angiotensinogen (AGT) ELISA Kit |
|
abx254811-96tests |
Abbexa |
96 tests |
EUR 801.6 |
|
|
 ELISA Kit) Chicken Angiotensinogen (AGT) ELISA Kit |
|
abx354753-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 ELISA Kit) Monkey Angiotensinogen (AGT) ELISA Kit |
|
abx354991-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 ELISA Kit) Pig Angiotensinogen (AGT) ELISA Kit |
|
abx355132-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 ELISA Kit) Rabbit Angiotensinogen (AGT) ELISA Kit |
|
abx355228-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 ELISA Kit) Cow Angiotensinogen (AGT) ELISA Kit |
|
abx514023-96tests |
Abbexa |
96 tests |
EUR 1093.2 |
|
|
 CLIA Kit) Rat Angiotensinogen (AGT) CLIA Kit |
|
20-abx492048 |
Abbexa |
-
EUR 10282.80
-
EUR 5472.00
-
EUR 1262.40
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
Mouse Angiotensinogen (AGT) ELISA Kit |
|
abx573245-96tests |
Abbexa |
96 tests |
EUR 858 |
|
|
Rat Angiotensinogen (AGT) ELISA Kit |
|
abx573648-96tests |
Abbexa |
96 tests |
EUR 858 |
|
|
Thus, this platform will help develop new monoclonal antibody therapeutics with excessive affinity and low immunogenicity. Moreover, anti-NGF mAb remedy is efficient in animal fashions of neuropathic most cancers ache. As regards sufferers with OA, though section II and section III medical trials with tanezumab led to ache discount, the security was not noticed in all these sufferers. Here, we overview the preclinical and medical research on anti-NGF mAb remedy in continual syndromes, dissect the function of NGF in ache transduction, and spotlight the usage of anti-NGF mAbs in people.
