The identification and management of monoclonal antibody (mAb) vital high quality attributes (CQAs) is a key element of high quality by design (QbD). In this work, fast peptide mapping and native intact cost variants evaluation have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis – mass spectrometry (CE-MS) platform. The ultrafast peptide mapping concurrently analyzed a number of CQAs, together with protein major construction, oxidation, deamidation, succinimide, C-terminal lysine (Lys) clipping, N-terminal cyclization, and glycosylation. The microfluidic CE-MS primarily based peptide mapping acquired outcomes comparable to standard however prolonged liquid chromatography – MS (LC-MS) primarily based method.
The native intact evaluation resolved mAb cost variants with a comparable decision as generally achieved using capillary isoelectric focusing (cIEF). Charge variants’ identities had been assigned primarily based on attribute mass shifts, information realized from peptide mapping, and adjustments in electrophoretic mobility. Major mAb glycoforms of every cost variants had been resolved and recognized within the deconvoluted mass spectra. Furthermore, a mannequin simulation was carried out to reconstruct intact deconvoluted mass spectra using peptide mapping outcomes.
The reconstructed and experimentally decided intact deconvoluted mass spectra had been extremely correlated, suggesting that our information collected on the peptide stage and intact stage had been constant and extremely comparable. Overall, the microfluidic CE-MS primarily based peptide mapping and native intact cost variants evaluation are high-throughput strategies which have nice potential to assist biopharmaceutical growth. Coronavirus illness 2019 (COVID-19) continues to emphasize the well being care system. Neutralizing monoclonal antibodies (mAbs) had been efficient in lowering COVID-19-related hospitalizations and emergency division (ED) visits of their respective medical trials.
Computational modeling of microfluidic information supplies high-throughput affinity estimates for monoclonal antibodies
Affinity measurement is a elementary step within the discovery of monoclonal antibodies (mAbs) and of antigens appropriate for vaccine growth. Innovative affinity assays are wanted as a result of low throughput and/or restricted dynamic vary of obtainable applied sciences. We mixed microfluidic expertise with quantum-mechanical scattering concept, so as to develop a high-throughput, broad-range methodology to measure affinity. Fluorescence depth profiles had been generated for out-of-equilibrium options of labelled mAbs and their antigen-binding fragments migrating alongside micro-columns with immobilized cognate antigen.
Affinity quantification was carried out by computational information evaluation primarily based on the Landau chance distribution. Experiments using a big selection of human or murine antibodies in opposition to bacterial or viral, protein or polysaccharide antigens, confirmed that every one the antibody-antigen seize profiles (n = 841) generated at completely different concentrations had been precisely described by the Landau distribution. A scale parameter W, proportional to the full-width-at-half-maximum of the seize profile, was proven to be unbiased of the antibody focus. Glycerol phosphate (GroP)-based teichoic acids (TAs) are antigenic cell-wall parts present in each enterococcus and staphylococcus species.
Their immunogenicity has been explored using each native and artificial buildings, however no particulars have but been reported on the structural foundation of their interplay with antibodies. This work represents the primary case research during which a monoclonal antibody, generated in opposition to an artificial TA, was developed and employed for molecular-level binding evaluation using TA microarrays, ELISA, SPR-analyses, and STD-NMR spectroscopy. However, these outcomes have but to be reproduced in a sensible setting following implementation of present US Food and Drug Administration (FDA) steering.
Method growth for the clearance research of the Pluronic F-68 nonionic surfactant used within the upstream means of monoclonal antibody manufacturing
Pluronic F-68 is a nonionic surfactant, which is usually used within the upstream means of biopharmaceutical manufacturing. However, the variety of analytical strategies developed for dedication of Pluronic F-68 within the in-process and drug substance samples of organic drug manufacturing course of is kind of low. The lack of chromophore teams on the molecule and the interference attributable to the excessive protein content material of the samples hamper evaluation. In this paper the event and qualification of a mixed-mode (MM) HPLC technique with charged aerosol detection is reported.
The technique allows the evaluation of samples with as much as 85 g/L protein focus. The vary of the tactic was set to 250-500 μg/mL, the place it was discovered to be correct (89-111 % restoration) and exact (0.8-3.2 % relative normal deviation). The excessive sensitivity of the tactic signifies that even decrease focus vary may be possible. The novel technique efficiently demonstrates Pluronic F-68 clearance throughout the downstream means of the monoclonal antibody manufacturing.
A novel and efficient method to generate germline-like monoclonal antibodies by integration of phage and mammalian cell show platforms
Phage show expertise permits for fast number of antibodies from the big repertoire of human antibody fragments displayed on phages. However, antibody fragments needs to be transformed to IgG for organic characterizations and affinity of antibodies obtained from phage show library is often not enough for environment friendly use in medical settings. Here, we describe a brand new method that mixes phage and mammalian cell show, enabling simultaneous affinity screening of full-length IgG antibodies. Using this technique, we efficiently obtained a novel germline-like anti-TIM-3 monoclonal antibody named m101, which was revealed to be a potent anti-TIM-Three therapeutic monoclonal antibody by way of in vitro and in vivo experiments, indicating its effectiveness and energy.
) Recombinant Angiotensinogen (AGT) |
|
4-RPA797Ra01 |
Cloud-Clone |
-
EUR 413.60
-
EUR 214.00
-
EUR 1276.00
-
EUR 492.00
-
EUR 884.00
-
EUR 340.00
-
EUR 3040.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Angiotensinogen expressed in: E.coli |
 Recombinant Human Angiotensinogen Protein |
|
RP01021 |
Abclonal |
5 μg |
EUR 183 |
 Angiotensinogen Peptide |
|
20-abx266414 |
Abbexa |
-
EUR 523.00
-
EUR 871.00
-
EUR 384.00
|
|
|
|
Angiotensinogen Peptide |
|
20-abx266467 |
Abbexa |
-
EUR 551.00
-
EUR 926.00
-
EUR 398.00
|
|
|
|
Angiotensinogen Peptide |
|
20-abx265209 |
Abbexa |
-
EUR 565.00
-
EUR 954.00
-
EUR 398.00
|
|
|
|
Angiotensinogen Peptide |
|
20-abx265535 |
Abbexa |
-
EUR 551.00
-
EUR 926.00
-
EUR 398.00
|
|
|
|
 Angiotensinogen Antibody |
|
49159-100ul |
SAB |
100ul |
EUR 333 |
Angiotensinogen Antibody |
|
49159-50ul |
SAB |
50ul |
EUR 239 |
 Angiotensinogen antibody |
|
10R-A130a |
Fitzgerald |
200 ul |
EUR 565 |
|
Description: Mouse monoclonal Angiotensinogen antibody |
Angiotensinogen antibody |
|
10R-A131a |
Fitzgerald |
200 ul |
EUR 457 |
|
Description: Mouse monoclonal Angiotensinogen antibody |
Angiotensinogen antibody |
|
70R-12752 |
Fitzgerald |
100 ul |
EUR 457 |
|
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody |
Angiotensinogen antibody |
|
70R-13411 |
Fitzgerald |
100 ul |
EUR 457 |
|
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody |
 Antibody) Angiotensinogen (AGT) Antibody |
|
20-abx301357 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx128540 |
Abbexa |
-
EUR 398.00
-
EUR 133.00
-
EUR 1107.00
-
EUR 537.00
-
EUR 314.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx110982 |
Abbexa |
|
|
|
|
 Angiotensinogen Rabbit mAb |
|
A11689-100ul |
Abclonal |
100 ul |
EUR 410 |
Angiotensinogen Rabbit mAb |
|
A11689-200ul |
Abclonal |
200 ul |
EUR 571 |
Angiotensinogen Rabbit mAb |
|
A11689-20ul |
Abclonal |
20 ul |
EUR 221 |
Angiotensinogen Rabbit mAb |
|
A11689-50ul |
Abclonal |
50 ul |
EUR 287 |
Angiotensinogen (AGT) Antibody |
|
20-abx101137 |
Abbexa |
-
EUR 398.00
-
EUR 133.00
-
EUR 1107.00
-
EUR 537.00
-
EUR 314.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101138 |
Abbexa |
-
EUR 411.00
-
EUR 133.00
-
EUR 1135.00
-
EUR 551.00
-
EUR 314.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101139 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1177.00
-
EUR 578.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx101140 |
Abbexa |
-
EUR 328.00
-
EUR 815.00
-
EUR 425.00
-
EUR 154.00
-
EUR 258.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody |
|
abx010360-100ul |
Abbexa |
100 ul |
EUR 411 |
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx004798 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
Angiotensinogen (AGT) Antibody |
|
abx033720-400ul |
Abbexa |
400 ul |
EUR 523 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033720-80l |
Abbexa |
80 µl |
EUR 286 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033721-400ul |
Abbexa |
400 ul |
EUR 523 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx033721-80l |
Abbexa |
80 µl |
EUR 286 |
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx171240 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx320213 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx322250 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
abx230393-100ug |
Abbexa |
100 ug |
EUR 509 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx230394-100ug |
Abbexa |
100 ug |
EUR 481 |
|
|
Angiotensinogen (AGT) Antibody |
|
abx230395-100ug |
Abbexa |
100 ug |
EUR 481 |
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx339646 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241726 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241946 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx241947 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx242324 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx214416 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx175400 |
Abbexa |
|
|
|
|
Angiotensinogen (AGT) Antibody |
|
20-abx211344 |
Abbexa |
|
|
|
|
 Human Angiotensinogen Antibody |
|
11013-05011 |
AssayPro |
150 ug |
EUR 217 |
 Angiotensinogen Conjugated Antibody |
|
C49159 |
SAB |
100ul |
EUR 397 |
) Human Angiotensinogen (AGT) |
|
1-CSB-EP001463HU1 |
Cusabio |
-
EUR 380.00
-
EUR 214.00
-
EUR 1309.00
-
EUR 560.00
-
EUR 873.00
-
EUR 262.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Human Angiotensinogen(AGT),partial expressed in E.coli |
) Eukaryotic Angiotensinogen (AGT) |
|
4-EPA797Mu61 |
Cloud-Clone |
-
EUR 466.46
-
EUR 228.00
-
EUR 1474.24
-
EUR 558.08
-
EUR 1016.16
-
EUR 375.00
-
EUR 3535.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Angiotensinogen expressed in: 293F cell |
Eukaryotic Angiotensinogen (AGT) |
|
4-EPA797Ra61 |
Cloud-Clone |
-
EUR 471.84
-
EUR 229.00
-
EUR 1494.40
-
EUR 564.80
-
EUR 1029.60
-
EUR 379.00
-
EUR 3586.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Angiotensinogen expressed in: 293F cell |
 anti- Angiotensinogen antibody |
|
FNab00393 |
FN Test |
100µg |
EUR 548.75 |
|
|
|
Description: Antibody raised against Angiotensinogen |
anti- Angiotensinogen antibody |
|
FNab00394 |
FN Test |
100µg |
EUR 505.25 |
|
|
|
Description: Antibody raised against Angiotensinogen |
anti- Angiotensinogen antibody |
|
FNab00395 |
FN Test |
100µg |
EUR 505.25 |
|
|
|
Description: Antibody raised against Angiotensinogen |
 Antibody (HRP)) Angiotensinogen (AGT) Antibody (HRP) |
|
20-abx306453 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Antibody (FITC)) Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx306454 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Antibody (Biotin)) Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx306455 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Anti-Angiotensinogen/AGT Antibody |
|
PA1643 |
BosterBio |
100ug/vial |
EUR 294 |
 Protein) Human Angiotensinogen (AGT) Protein |
|
20-abx065351 |
Abbexa |
-
EUR 746.00
-
EUR 300.00
-
EUR 2332.00
-
EUR 885.00
-
EUR 523.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Mouse Angiotensinogen (AGT) Protein |
|
20-abx065352 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Rat Angiotensinogen (AGT) Protein |
|
20-abx065353 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Human Angiotensinogen (AGT) Protein |
|
20-abx065354 |
Abbexa |
-
EUR 746.00
-
EUR 300.00
-
EUR 2332.00
-
EUR 885.00
-
EUR 523.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Anti-Angiotensinogen/AGT Antibody |
|
A02103-1 |
BosterBio |
100ug/vial |
EUR 334 |
, human) Angiotensinogen (1-14), human |
|
5-00697 |
CHI Scientific |
4 x 5mg |
Ask for price |
, Porcine) Angiotensinogen (1-14), Porcine |
|
5-00698 |
CHI Scientific |
4 x 5mg |
Ask for price |
 , Rat) Angiotensinogen (1-14) , Rat |
|
5-00699 |
CHI Scientific |
4 x 5mg |
Ask for price |
 Antibody Pair) Angiotensinogen (AGT) Antibody Pair |
|
20-abx370425 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
|
Angiotensinogen (AGT) Antibody Pair |
|
20-abx370604 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
|
Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx273972 |
Abbexa |
-
EUR 453.00
-
EUR 244.00
-
EUR 1316.00
-
EUR 634.00
-
EUR 342.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (FITC) |
|
20-abx274115 |
Abbexa |
-
EUR 467.00
-
EUR 244.00
-
EUR 1386.00
-
EUR 648.00
-
EUR 356.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx272741 |
Abbexa |
-
EUR 425.00
-
EUR 230.00
-
EUR 1219.00
-
EUR 592.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Angiotensinogen (AGT) Antibody (Biotin) |
|
20-abx273211 |
Abbexa |
-
EUR 453.00
-
EUR 244.00
-
EUR 1288.00
-
EUR 620.00
-
EUR 342.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Mouse Angiotensinogen (AGT) Protein |
|
20-abx651467 |
Abbexa |
-
EUR 648.00
-
EUR 272.00
-
EUR 1984.00
-
EUR 773.00
-
EUR 467.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Rat Angiotensinogen (AGT) Protein |
|
20-abx651468 |
Abbexa |
-
EUR 662.00
-
EUR 272.00
-
EUR 2012.00
-
EUR 787.00
-
EUR 481.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Human Angiotensinogen ELISA kit |
|
E01A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensinogen ELISA kit |
|
E01A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensinogen ELISA kit |
|
E01A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Dog Angiotensinogen ELISA kit |
|
E08A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensinogen ELISA kit |
|
E08A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensinogen ELISA kit |
|
E08A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rabbit Angiotensinogen ELISA kit |
|
E04A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensinogen ELISA kit |
|
E04A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensinogen ELISA kit |
|
E04A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Monkey Angiotensinogen ELISA kit |
|
E09A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensinogen ELISA kit |
|
E09A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensinogen ELISA kit |
|
E09A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rat Angiotensinogen ELISA kit |
|
E02A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensinogen ELISA kit |
|
E02A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensinogen ELISA kit |
|
E02A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Pig Angiotensinogen ELISA kit |
|
E07A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensinogen ELISA kit |
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E07A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensinogen ELISA kit |
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E07A0497-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
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Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Goat Angiotensinogen ELISA kit |
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E06A0497-192T |
BlueGene |
192 tests |
EUR 1270 |
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Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensinogen ELISA kit |
|
E06A0497-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
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Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Thus, this platform will help develop new monoclonal antibody therapeutics with excessive affinity and low immunogenicity. Moreover, anti-NGF mAb remedy is efficient in animal fashions of neuropathic most cancers ache. As regards sufferers with OA, though section II and section III medical trials with tanezumab led to ache discount, the security was not noticed in all these sufferers. Here, we overview the preclinical and medical research on anti-NGF mAb remedy in continual syndromes, dissect the function of NGF in ache transduction, and spotlight the usage of anti-NGF mAbs in people.
