Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS

Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS

Posted on by Cody

The identification and management of monoclonal antibody (mAb) vital high quality attributes (CQAs) is a key element of high quality by design (QbD). In this work, fast peptide mapping and native intact cost variants evaluation have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis – mass spectrometry (CE-MS) platform. The ultrafast peptide mapping concurrently analyzed a number of CQAs, together with protein major construction, oxidation, deamidation, succinimide, C-terminal lysine (Lys) clipping, N-terminal cyclization, and glycosylation. The microfluidic CE-MS primarily based peptide mapping acquired outcomes comparable to standard however prolonged liquid chromatography – MS (LC-MS) primarily based method.

The native intact evaluation resolved mAb cost variants with a comparable decision as generally achieved using capillary isoelectric focusing (cIEF). Charge variants’ identities had been assigned primarily based on attribute mass shifts, information realized from peptide mapping, and adjustments in electrophoretic mobility. Major mAb glycoforms of every cost variants had been resolved and recognized within the deconvoluted mass spectra. Furthermore, a mannequin simulation was carried out to reconstruct intact deconvoluted mass spectra using peptide mapping outcomes.

The reconstructed and experimentally decided intact deconvoluted mass spectra had been extremely correlated, suggesting that our information collected on the peptide stage and intact stage had been constant and extremely comparable. Overall, the microfluidic CE-MS primarily based peptide mapping and native intact cost variants evaluation are high-throughput strategies which have nice potential to assist biopharmaceutical growth. Coronavirus illness 2019 (COVID-19) continues to emphasize the well being care system. Neutralizing monoclonal antibodies (mAbs) had been efficient in lowering COVID-19-related hospitalizations and emergency division (ED) visits of their respective medical trials.

Computational modeling of microfluidic information supplies high-throughput affinity estimates for monoclonal antibodies

Affinity measurement is a elementary step within the discovery of monoclonal antibodies (mAbs) and of antigens appropriate for vaccine growth. Innovative affinity assays are wanted as a result of low throughput and/or restricted dynamic vary of obtainable applied sciences. We mixed microfluidic expertise with quantum-mechanical scattering concept, so as to develop a high-throughput, broad-range methodology to measure affinity. Fluorescence depth profiles had been generated for out-of-equilibrium options of labelled mAbs and their antigen-binding fragments migrating alongside micro-columns with immobilized cognate antigen.

Affinity quantification was carried out by computational information evaluation primarily based on the Landau chance distribution. Experiments using a big selection of human or murine antibodies in opposition to bacterial or viral, protein or polysaccharide antigens, confirmed that every one the antibody-antigen seize profiles (n = 841) generated at completely different concentrations had been precisely described by the Landau distribution. A scale parameter W, proportional to the full-width-at-half-maximum of the seize profile, was proven to be unbiased of the antibody focus. Glycerol phosphate (GroP)-based teichoic acids (TAs) are antigenic cell-wall parts present in each enterococcus and staphylococcus species.

Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS

Their immunogenicity has been explored using each native and artificial buildings, however no particulars have but been reported on the structural foundation of their interplay with antibodies. This work represents the primary case research during which a monoclonal antibody, generated in opposition to an artificial TA, was developed and employed for molecular-level binding evaluation using TA microarrays, ELISA, SPR-analyses, and STD-NMR spectroscopy. However, these outcomes have but to be reproduced in a sensible setting following implementation of present US Food and Drug Administration (FDA) steering.

Method growth for the clearance research of the Pluronic F-68 nonionic surfactant used within the upstream means of monoclonal antibody manufacturing

Pluronic F-68 is a nonionic surfactant, which is usually used within the upstream means of biopharmaceutical manufacturing. However, the variety of analytical strategies developed for dedication of Pluronic F-68 within the in-process and drug substance samples of organic drug manufacturing course of is kind of low. The lack of chromophore teams on the molecule and the interference attributable to the excessive protein content material of the samples hamper evaluation. In this paper the event and qualification of a mixed-mode (MM) HPLC technique with charged aerosol detection is reported.

The technique allows the evaluation of samples with as much as 85 g/L protein focus. The vary of the tactic was set to 250-500 μg/mL, the place it was discovered to be correct (89-111 % restoration) and exact (0.8-3.2 % relative normal deviation). The excessive sensitivity of the tactic signifies that even decrease focus vary may be possible. The novel technique efficiently demonstrates Pluronic F-68 clearance throughout the downstream means of the monoclonal antibody manufacturing.

A novel and efficient method to generate germline-like monoclonal antibodies by integration of phage and mammalian cell show platforms

Phage show expertise permits for fast number of antibodies from the big repertoire of human antibody fragments displayed on phages. However, antibody fragments needs to be transformed to IgG for organic characterizations and affinity of antibodies obtained from phage show library is often not enough for environment friendly use in medical settings. Here, we describe a brand new method that mixes phage and mammalian cell show, enabling simultaneous affinity screening of full-length IgG antibodies. Using this technique, we efficiently obtained a novel germline-like anti-TIM-3 monoclonal antibody named m101, which was revealed to be a potent anti-TIM-Three therapeutic monoclonal antibody by way of in vitro and in vivo experiments, indicating its effectiveness and energy.

Recombinant Angiotensinogen (AGT)
4-RPA797Ra01
  • EUR 496.32
  • EUR 256.80
  • EUR 1531.20
  • EUR 590.40
  • EUR 1060.80
  • EUR 408.00
  • EUR 3648.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Angiotensinogen expressed in: E.coli

Recombinant Human Angiotensinogen Protein
RP01021 5 μg
EUR 219.6

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-10ug 10ug
EUR 242.4
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-1mg 1mg
EUR 2983.2
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-500ug 500ug
EUR 2106
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-1mg
QP5624-ec-1mg 1mg
EUR 1958.4

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-100ug
QP5624-ec-100ug 100ug
EUR 489.6

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-10ug
QP5624-ec-10ug 10ug
EUR 240

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-200ug
QP5624-ec-200ug 200ug
EUR 760.8

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-500ug
QP5624-ec-500ug 500ug
EUR 1272

Recombinant Human Angiotensinogen/ SerpinA8/ AGT Protein, His-SUMO, E.coli-50ug
QP5624-ec-50ug 50ug
EUR 315.6

Angiotensinogen (1-14) , Rat
5-00699 4 x 5mg Ask for price

Angiotensinogen (1- 13)
5-00696 4 x 5mg Ask for price

Angiotensinogen Peptide
20-abx265209
  • EUR 678.00
  • EUR 1144.80
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx265535
  • EUR 661.20
  • EUR 1111.20
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx266414
  • EUR 627.60
  • EUR 1045.20
  • EUR 460.80
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen Peptide
20-abx266467
  • EUR 661.20
  • EUR 1111.20
  • EUR 477.60
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensinogen (1-14), human
5-00697 4 x 5mg Ask for price

Angiotensinogen (1-14), human
HY-P1486 10mg
EUR 763.2

Angiotensinogen antibody
10R-A130a 200 ul
EUR 678
Description: Mouse monoclonal Angiotensinogen antibody

Angiotensinogen antibody
10R-A131a 200 ul
EUR 548.4
Description: Mouse monoclonal Angiotensinogen antibody

Angiotensinogen antibody
70R-12752 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody

Angiotensinogen antibody
70R-13411 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Angiotensinogen antibody

Angiotensinogen Antibody
49159-100ul 100ul
EUR 399.6

Angiotensinogen Antibody
49159-50ul 50ul
EUR 286.8

Angiotensinogen Antibody
R32681 100ug
EUR 356.15
Description: AGT (Angiotensinogen), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Angiotensinogen Antibody
RQ6926 100 ug
EUR 356.15
Description: AGT (ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Angiotensinogen Antibody
RQ4852 100ul
EUR 356.15
Description: Angiotensinogen is an essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [UniProt]

Angiotensinogen (1-14), Porcine
5-00698 4 x 5mg Ask for price

Human Angiotensinogen (AGT)
1-CSB-EP001463HU1
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Angiotensinogen(AGT),partial expressed in E.coli

Angiotensinogen Rabbit mAb
A11689-100ul 100 ul
EUR 492

Angiotensinogen Rabbit mAb
A11689-200ul 200 ul
EUR 685.2

Angiotensinogen Rabbit mAb
A11689-20ul 20 ul
EUR 265.2

Angiotensinogen Rabbit mAb
A11689-50ul 50 ul
EUR 344.4

Angiotensinogen (AGT) Antibody
20-abx242324
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx230393-100ug 100 ug
EUR 610.8

Angiotensinogen (AGT) Antibody
abx230394-100ug 100 ug
EUR 577.2

Angiotensinogen (AGT) Antibody
abx230395-100ug 100 ug
EUR 577.2

Angiotensinogen (AGT) Antibody
20-abx241726
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx241946
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx241947
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx175400
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Angiotensinogen (AGT) Antibody
20-abx171240
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Angiotensinogen (AGT) Antibody
20-abx214416
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx211344
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx322250
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx110982
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx033720-400ul 400 ul
EUR 627.6

Angiotensinogen (AGT) Antibody
abx033720-80l 80 µl
EUR 343.2

Angiotensinogen (AGT) Antibody
abx033721-400ul 400 ul
EUR 627.6

Angiotensinogen (AGT) Antibody
abx033721-80l 80 µl
EUR 343.2

Angiotensinogen (AGT) Antibody
20-abx101137
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101138
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101139
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx101140
  • EUR 393.60
  • EUR 978.00
  • EUR 510.00
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiotensinogen (AGT) Antibody
20-abx128540
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen, Human Plasma
ATN15-N-100 100 ug
EUR 270

Angiotensinogen (AGT) Antibody
20-abx320213
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx339646
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
20-abx004798
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Angiotensinogen (AGT) Antibody
abx010360-100ul 100 ul
EUR 493.2

Angiotensinogen (AGT) Antibody
20-abx301357
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiotensinogen Antibody / AGT
R30727 100ug
EUR 419

anti- Angiotensinogen antibody
FNab00393 100µg
EUR 658.5
Description: Antibody raised against Angiotensinogen

anti- Angiotensinogen antibody
FNab00394 100µg
EUR 606.3
Description: Antibody raised against Angiotensinogen

anti- Angiotensinogen antibody
FNab00395 100µg
EUR 606.3
Description: Antibody raised against Angiotensinogen

Rat angiotensinogen ELISA kit
55R-2262 1 kit
EUR 1647.6
Description: Rat angiotensinogen ELISA kit for use in research

Rat Angiotensinogen ELISA kit
E02A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensinogen ELISA kit
E07A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensinogen ELISA kit
E08A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen Antibody
11013-05011 150 ug
EUR 260.4

Eukaryotic Angiotensinogen (AGT)
4-EPA797Mu61
  • EUR 559.75
  • EUR 273.60
  • EUR 1769.09
  • EUR 669.70
  • EUR 1219.39
  • EUR 450.00
  • EUR 4242.72
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiotensinogen expressed in: 293F cell

Eukaryotic Angiotensinogen (AGT)
4-EPA797Ra61
  • EUR 566.21
  • EUR 274.80
  • EUR 1793.28
  • EUR 677.76
  • EUR 1235.52
  • EUR 454.80
  • EUR 4303.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Angiotensinogen expressed in: 293F cell

Goat Angiotensinogen ELISA kit
E06A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensinogen ELISA kit
E06A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensinogen ELISA kit
E06A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Acetyl Angiotensinogen (1-14), porcine
A1034-10 10 mg
EUR 164.4
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Acetyl Angiotensinogen (1-14), porcine
A1034-25 25 mg
EUR 205.2
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Acetyl Angiotensinogen (1-14), porcine
A1034-5 5 mg
EUR 122.4
Description: Acetyl Angiotensinogen (1-14),porcine, (C87H125N21O21) is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH, MW= 1801.5.

Rat Angiotensinogen (AGT) Protein
20-abx065353
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Angiotensinogen (AGT) Protein
20-abx651468
  • EUR 794.40
  • EUR 326.40
  • EUR 2414.40
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen ELISA kit
E03A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensinogen ELISA kit
E03A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensinogen ELISA kit
E03A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensinogen ELISA kit
E01A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Angiotensinogen (AGT) Antibody (HRP)
20-abx306453
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monkey Angiotensinogen ELISA kit
E09A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensinogen ELISA kit
E09A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensinogen ELISA kit
E09A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensinogen ELISA kit
E04A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen (AGT) CLIA Kit
abx195130-96tests 96 tests
EUR 990

Rat Angiotensinogen (AGT) CLIA Kit
20-abx492048
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Angiotensinogen (AGT) Antibody Pair
20-abx370425
  • EUR 1914.00
  • EUR 1228.80
  • 10 × 96 tests
  • 5 × 96 tests

Angiotensinogen (AGT) Antibody Pair
20-abx370604
  • EUR 2047.20
  • EUR 1312.80
  • 10 × 96 tests
  • 5 × 96 tests

Human Angiotensinogen (AGT) Protein
20-abx065351
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen (AGT) Protein
20-abx065352
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Angiotensinogen (AGT) Protein
20-abx065354
  • EUR 895.20
  • EUR 360.00
  • EUR 2798.40
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Angiotensinogen (AGT) Protein
20-abx651467
  • EUR 777.60
  • EUR 326.40
  • EUR 2380.80
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx273972
  • EUR 543.60
  • EUR 292.80
  • EUR 1579.20
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx274115
  • EUR 560.40
  • EUR 292.80
  • EUR 1663.20
  • EUR 777.60
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensinogen (AGT) Antibody (FITC)
20-abx306454
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Angiotensinogen (AGT) ELISA Kit
abx256349-96tests 96 tests
EUR 801.6

Rat Angiotensinogen (AGT) ELISA Kit
20-abx155199
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Angiotensinogen (AGT) ELISA Kit
abx573648-96tests 96 tests
EUR 858

Cow Angiotensinogen (AGT) ELISA Kit
abx514023-96tests 96 tests
EUR 1093.2

Pig Angiotensinogen (AGT) ELISA Kit
abx355132-96tests 96 tests
EUR 990

Rat angiotensinogen,aGT ELISA Kit
CN-01790R1 96T
EUR 536.4

Rat angiotensinogen,aGT ELISA Kit
CN-01790R2 48T
EUR 355.2

Rat Angiotensinogen (AGT) ELISA Kit
DLR-AGT-Ra-48T 48T
EUR 544.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Angiotensinogen (AGT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Angiotensinogen (AGT) ELISA Kit
DLR-AGT-Ra-96T 96T
EUR 704.4
Description: A sandwich quantitative ELISA assay kit for detection of Rat Angiotensinogen (AGT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat angiotensinogen (aGT) ELISA Kit
CSB-E08565r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat angiotensinogen (aGT) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat angiotensinogen (aGT) ELISA Kit
1-CSB-E08565r
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat angiotensinogen (aGT) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Agt(Angiotensinogen) ELISA Kit
ER0371 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.938 ng/ml

Rat Agt/ Angiotensinogen ELISA Kit
E0038Ra 1 Kit
EUR 685.2

Rat angiotensinogen(aGT)ELISA Kit
GA-E0665RT-48T 48T
EUR 447.6

Thus, this platform will help develop new monoclonal antibody therapeutics with excessive affinity and low immunogenicity. Moreover, anti-NGF mAb remedy is efficient in animal fashions of neuropathic most cancers ache. As regards sufferers with OA, though section II and section III medical trials with tanezumab led to ache discount, the security was not noticed in all these sufferers. Here, we overview the preclinical and medical research on anti-NGF mAb remedy in continual syndromes, dissect the function of NGF in ache transduction, and spotlight the usage of anti-NGF mAbs in people.

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