Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1

Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1

Posted on by Cody

Aspergillus flavus is a major fungal pathogen of vegetation and an opportunistic pathogen of people. In addition to the direct affect of an infection, it produces immunosuppressive and carcinogenic aflatoxins. The early detection of A. flavus is due to this fact essential to diagnose and monitor fungal an infection, to stop aflatoxin contamination of meals and feed, and for efficient antifungal remedy. Aspergillus-specific monoclonal antibodies (mAbs) are promising as diagnostic and therapeutic reagents for the monitoring and therapy of Aspergillus infections, respectively.

However, A. flavus has a posh cell wall composition and dynamic morphology, hindering the discovery of mAbs with well-characterized targets. Here we describe the technology and detailed characterization of mAb5.52 (IgG2aκ) and mAb17.15 (IgG1κ), which bind particularly to the extremely immunogenic cell wall antigen A. flavus mannoprotein 1 (Aflmp1). Both mAbs have been generated utilizing hybridoma know-how following the immunization of mice with a recombinant truncated model of Aflmp1 (ExD, together with the homologous CR4 area) produced in micro organism. We present that mAb5.52 and mAb17.15 bind particularly to A. flavus and A. parasiticus cell wall fragments (CWFs), with no cross-reaction to CWFs from different fungal pathogens.

Immunofluorescence microscopy revealed that each mAbs bind to the floor of Aspergillus hyphae and that mAb17.15 additionally binds to spores. The epitope for each mAbs is localized inside the CR4 area of the Aflmp1 protein. These Aspergillus-specific mAbs could also be helpful for the early detection of fungal an infection in meals/feed crops, for serodiagnosis in sufferers with invasive aspergillosis attributable to A. flavus an infection and for the improvement of antibody-expressing disease-resistant crops. The epidermal development issue receptor (EGFR) is a tyrosine kinase receptor that performs an necessary function in regular epidermal cell physiology.

EGFR is overexpressed in most cancers cells and has a quantity of mutations that implicate tumor malignancy, improvement, and poor affected person prognosis; thus, EGFR is a pretty goal for most cancers remedy. At current, anti-EGFR monoclonal antibodies (mAbs) have been authorized and are used for treating sufferers with a range of EGFR-expressing cancers.

Tubulointerstitial nephritis in antineutrophil cytoplasmic antibody-associated vasculitis with monoclonal gammopathy

Isolated tubulointerstitial nephritis (TIN) with out glomerular crescent formation is a uncommon manifestation of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Some sufferers with monoclonal gammopathy of undetermined significance current with renal issues as a result of serum monoclonal protein. Here, we current a case of TIN presumably attributable to AAV with monoclonal gammopathy. Laboratory knowledge revealed acute kidney damage, elevated C-reactive protein (CRP) and ANCA titers, and elevated tubular damage markers. Renal biopsy revealed TIN with no obvious glomerular lesion. The findings of peritubular capillaritis and tubulitis indicated that AAV had contributed to the improvement of TIN.

However, in situ hybridization for free mild chains revealed kappa mild chain restriction, indicating that the involvement of monoclonal gammopathy in the pathogenesis of TIN stays potential. The affected person additionally developed ophthalmic neuropathy, in all probability attributable to AAV. Oral prednisone (0.6 mg/kg/day) administration improved each the ocular signs and the laboratory parameters. Our case demonstrated that the concurrence of AAV and monoclonal gammopathy might pose a diagnostic dilemma in distinguishing the trigger of TIN. Besides, some studies recommend an affiliation between AAV and monoclonal gammopathy, though direct proof is missing. Further analysis is required to determine this affiliation.

CD44 capabilities as a major hyaluronan receptor on most cell varieties, with roles in cell adhesion, migration, proliferation, differentiation, and survival. The CD44 gene includes 20 exons, with different splicing producing many various isoforms. CD44 variant isoforms exhibit tissue-specific expression patterns and have been studied as therapeutic targets for a number of cancers; due to this fact, anti-CD44 monoclonal antibodies (mAbs) are helpful for investigating CD44 expression in varied cancers.

Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1

Isolation and characterization of porcine monoclonal antibodies revealed two distinct serotype-independent epitopes on VP2 of foot-and-mouth illness virus

Pigs are prone to foot-and-mouth illness virus (FMDV), and the humoral immune response performs a vital function in safety in opposition to FMDV an infection. However, little info is obtainable about FMDV-specific mAbs derived from single B cells of pigs. This research aimed to find out the antigenic options of FMDV which are acknowledged by antibodies from pigs. Therefore, a panel of pig-derived mAbs in opposition to FMDV have been developed utilizing fluorescence-based single B cell antibody know-how. Western blotting revealed that three of the antibodies acknowledged conserved antigen epitopes on capsid protein VP2, and exhibited broad reactivity in opposition to each FMDV serotypes A and O.

Recombinant Rat Angiotensinogen (Agt)
MBS950608-01mgYeast 0.1mg(Yeast)
EUR 1270

Recombinant Angiotensinogen (AGT)
MBS2010533-001mg 0.01mg
EUR 180

Recombinant Angiotensinogen (AGT)
MBS2010533-005mg 0.05mg
EUR 330

Recombinant Angiotensinogen (AGT)
MBS2010533-01mg 0.1mg
EUR 500

Recombinant Angiotensinogen (AGT)
MBS2010533-02mg 0.2mg
EUR 615

Recombinant Angiotensinogen (AGT)
MBS2010533-05mg 0.5mg
EUR 1170

Recombinant Angiotensinogen (AGT)
MBS2010720-001mg 0.01mg
EUR 180

Recombinant Angiotensinogen (AGT)
MBS2010720-005mg 0.05mg
EUR 330

Recombinant Angiotensinogen (AGT)
MBS2010720-01mg 0.1mg
EUR 500

Recombinant Angiotensinogen (AGT)
MBS2010720-02mg 0.2mg
EUR 615

Recombinant Angiotensinogen (AGT)
MBS2010720-05mg 0.5mg
EUR 1170

Recombinant Angiotensinogen (AGT)
MBS2009330-001mg 0.01mg
EUR 155

Recombinant Angiotensinogen (AGT)
MBS2009330-005mg 0.05mg
EUR 260

Recombinant Angiotensinogen (AGT)
MBS2009330-01mg 0.1mg
EUR 375

Recombinant Angiotensinogen (AGT)
MBS2009330-02mg 0.2mg
EUR 460

Recombinant Angiotensinogen (AGT)
MBS2009330-05mg 0.5mg
EUR 860

Recombinant Angiotensinogen (AGT)
MBS2011101-001mg 0.01mg
EUR 155

Recombinant Angiotensinogen (AGT)
MBS2011101-005mg 0.05mg
EUR 260

Recombinant Angiotensinogen (AGT)
MBS2011101-01mg 0.1mg
EUR 375

Recombinant Angiotensinogen (AGT)
MBS2011101-02mg 0.2mg
EUR 460

Recombinant Angiotensinogen (AGT)
MBS2011101-05mg 0.5mg
EUR 860

Recombinant Angiotensinogen (AGT)
RPU56827-100ug 100ug
EUR 470.4

Recombinant Angiotensinogen (AGT)
RPU56827-1mg 1mg
EUR 2184

Recombinant Angiotensinogen (AGT)
RPU56827-50ug 50ug
EUR 385

Recombinant Angiotensinogen (AGT)
RPU40285-100ug 100ug
EUR 599.5

Recombinant Angiotensinogen (AGT)
RPU40285-1mg 1mg
EUR 2653.3

Recombinant Angiotensinogen (AGT)
RPU40285-50ug 50ug
EUR 480.7

Recombinant Angiotensinogen (AGT)
RPU40286-100ug 100ug
EUR 431.2

Recombinant Angiotensinogen (AGT)
RPU40286-1mg 1mg
EUR 1911

Recombinant Angiotensinogen (AGT)
RPU40286-50ug 50ug
EUR 346.5

Recombinant Angiotensinogen (AGT)
RPU40287-100ug 100ug
EUR 431.2

Recombinant Angiotensinogen (AGT)
RPU40287-1mg 1mg
EUR 1911

Recombinant Angiotensinogen (AGT)
RPU40287-50ug 50ug
EUR 346.5

Recombinant Angiotensinogen (AGT)
RPU40288-100ug 100ug
EUR 599.5

Recombinant Angiotensinogen (AGT)
RPU40288-1mg 1mg
EUR 2653.3

Recombinant Angiotensinogen (AGT)
RPU40288-50ug 50ug
EUR 480.7

Recombinant Angiotensinogen (AGT)
RPA797Hu01 10ug
EUR 194

Recombinant Angiotensinogen (AGT)
4-RPA797Hu01
  • Ask for price
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  • 5 mg
  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
Description: Recombinant Human Angiotensinogen expressed in: E.coli

Recombinant Angiotensinogen (AGT)
RPA797Hu02 10ug
EUR 194

Recombinant Angiotensinogen (AGT)
4-RPA797Hu02
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  • 5 mg
  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
Description: Recombinant Human Angiotensinogen expressed in: E.coli

Recombinant Angiotensinogen (AGT)
RPA797Mu01 10ug
EUR 140

Recombinant Angiotensinogen (AGT)
4-RPA797Mu01
  • Ask for price
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  • Ask for price
  • 5 mg
  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
Description: Recombinant Mouse Angiotensinogen expressed in: E.coli

Recombinant Angiotensinogen (AGT)
RPA797Ra01 10ug
EUR 140

Recombinant Angiotensinogen (AGT)
4-RPA797Ra01
  • Ask for price
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  • Ask for price
  • 5 mg
  • 10ug
  • 50ug
  • 100 ug
  • 200 ug
  • 500 ug
  • 1 mg
Description: Recombinant Rat Angiotensinogen expressed in: E.coli

Recombinant Rat Angiotensinogen/AGT protein (His tag)
MBS2571490-002mg 0.02mg
EUR 305

Recombinant Rat Angiotensinogen/AGT protein (His tag)
MBS2571490-01mg 0.1mg
EUR 490

Recombinant Rat Angiotensinogen/AGT protein (His tag)
MBS2571490-5x01mg 5x0.1mg
EUR 2185

Recombinant Rat Angiotensinogen/AGT protein (His tag)
PDMR100022-100ug 100ug
EUR 499
Description: Rat

Recombinant Rat Angiotensinogen/AGT protein (His tag)
PDMR100022-20ug 20ug
EUR 299
Description: Rat

Recombinant Human Angiotensinogen
MBS954800-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Human Angiotensinogen
MBS954800-002mgMammalianCell 0.02mg(Mammalian-Cell)
EUR 1585

Recombinant Human Angiotensinogen
MBS954800-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Human Angiotensinogen
MBS954800-01mgBaculovirus 0.1mg(Baculovirus)
EUR 1900

Recombinant Human Angiotensinogen
MBS954800-01mgYeast 0.1mg(Yeast)
EUR 1270

Recombinant Horse Angiotensinogen (AGT)
MBS718491-005mgBaculovirus 0.05mg(Baculovirus)
EUR 875

Recombinant Horse Angiotensinogen (AGT)
MBS718491-005mgEColi 0.05mg(E-Coli)
EUR 490

Recombinant Horse Angiotensinogen (AGT)
MBS718491-005mgYeast 0.05mg(Yeast)
EUR 695

Recombinant Horse Angiotensinogen (AGT)
MBS718491-02mgEColi 0.2mg(E-Coli)
EUR 645

Recombinant Horse Angiotensinogen (AGT)
MBS718491-05mgEColi 0.5mg(E-Coli)
EUR 700

Recombinant Sheep Angiotensinogen (AGT)
MBS948831-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Sheep Angiotensinogen (AGT)
MBS948831-002mgEColi 0.02mg(E-Coli)
EUR 1010

Recombinant Sheep Angiotensinogen (AGT)
MBS948831-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Sheep Angiotensinogen (AGT)
MBS948831-01mgEColi 0.1mg(E-Coli)
EUR 1180

Recombinant Sheep Angiotensinogen (AGT)
MBS948831-01mgYeast 0.1mg(Yeast)
EUR 1270

Recombinant Mouse Angiotensinogen (Agt)
MBS949091-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Mouse Angiotensinogen (Agt)
MBS949091-002mgEColi 0.02mg(E-Coli)
EUR 1010

Recombinant Mouse Angiotensinogen (Agt)
MBS949091-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Mouse Angiotensinogen (Agt)
MBS949091-01mgEColi 0.1mg(E-Coli)
EUR 1180

Recombinant Mouse Angiotensinogen (Agt)
MBS949091-01mgYeast 0.1mg(Yeast)
EUR 1270

Angiotensinogen Recombinant Rabbit mAb
BS48837 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Angiotensinogen Recombinant Rabbit mAb
BS49196 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Angiotensinogen Recombinant Rabbit mAb
BS45966 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Angiotensinogen Recombinant Rabbit mAb
BS47031 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Angiotensinogen Recombinant Rabbit mAb
BS47858 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Recombinant Bovine Angiotensinogen (AGT)
MBS953438-002mgBaculovirus 0.02mg(Baculovirus)
EUR 935

Recombinant Bovine Angiotensinogen (AGT)
MBS953438-002mgEColi 0.02mg(E-Coli)
EUR 485

Recombinant Bovine Angiotensinogen (AGT)
MBS953438-002mgYeast 0.02mg(Yeast)
EUR 705

Recombinant Bovine Angiotensinogen (AGT)
MBS953438-01mgEColi 0.1mg(E-Coli)
EUR 575

Recombinant Bovine Angiotensinogen (AGT)
MBS953438-01mgYeast 0.1mg(Yeast)
EUR 805

Recombinant Chicken Angiotensinogen (AGT)
MBS964225-005mgBaculovirus 0.05mg(Baculovirus)
EUR 875

Recombinant Chicken Angiotensinogen (AGT)
MBS964225-005mgEColi 0.05mg(E-Coli)
EUR 485

Recombinant Chicken Angiotensinogen (AGT)
MBS964225-005mgYeast 0.05mg(Yeast)
EUR 705

Recombinant Chicken Angiotensinogen (AGT)
MBS964225-02mgEColi 0.2mg(E-Coli)
EUR 635

Recombinant Chicken Angiotensinogen (AGT)
MBS964225-05mgEColi 0.5mg(E-Coli)
EUR 700

Recombinant Human Angiotensinogen Protein
MBS9141858-002mg 0.02mg
EUR 195

Recombinant Human Angiotensinogen Protein
MBS9141858-005mg 0.05mg
EUR 280

Recombinant Human Angiotensinogen Protein
MBS9141858-01mg 0.1mg
EUR 385

Recombinant Human Angiotensinogen Protein
MBS9141858-5x01mg 5x0.1mg
EUR 1555

Recombinant Human Angiotensinogen (AGT), partial
CSB-EP001463HU1 508 mg Ask for price

Recombinant Human Angiotensinogen (AGT), partial
CSB-EP001463HU1-20ug 20ug Ask for price
Description: 44-427aa

Recombinant Human Angiotensinogen(AGT),partial
AP76501 1mg
EUR 1978

Recombinant Human Angiotensinogen (AGT), partial
MBS7110813-002mgEColi 0.02mg(E-Coli)
EUR 255

Recombinant Human Angiotensinogen (AGT), partial
MBS7110813-01mgEColi 0.1mg(E-Coli)
EUR 405

Recombinant Human Angiotensinogen (AGT), partial
MBS7110813-1mgEColi 1mg(E-Coli)
EUR 1425

Recombinant Human Angiotensinogen (AGT), partial
MBS7110813-5x1mgEColi 5x1mg(E-Coli)
EUR 6215

Recombinant Human Angiotensinogen/AGT Protein
RP01021 5 μg
EUR 209.01

Recombinant Mouse Angiotensinogen/AGT Protein
RP01621 100μg
EUR 41.8

Recombinant Human Angiotensinogen, His-tagged
AGT-2182H 10ug
EUR 238.4
Description: Avoid repeated freeze/thaw cycles. Store at 2-8-deg-C for one month. Aliquot and store at -80-deg-C for 12 months.

Angiotensinogen (1-14) , Rat
5-00699 4 x 5mg
EUR 319.41
Description: Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Tyr-Tyr-Ser

Angiotensinogen (1-14) (Rat)
MBS8246103-10mg 10mg
EUR 845

Angiotensinogen (1-14) (Rat)
MBS8246103-1mg 1mg
EUR 295

Angiotensinogen (1-14) (Rat)
MBS8246103-5mg 5mg
EUR 595

Angiotensinogen (1-14) (Rat)
MBS8246103-5x10mg 5x10mg
EUR 3710

Recombinant Pan troglodytes Angiotensinogen (AGT)
MBS1474316-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Pan troglodytes Angiotensinogen (AGT)
MBS1474316-002mgEColi 0.02mg(E-Coli)
EUR 1010

Recombinant Pan troglodytes Angiotensinogen (AGT)
MBS1474316-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Pan troglodytes Angiotensinogen (AGT)
MBS1474316-01mgEColi 0.1mg(E-Coli)
EUR 1180

Recombinant Pan troglodytes Angiotensinogen (AGT)
MBS1474316-01mgYeast 0.1mg(Yeast)
EUR 1270

Angiotensinogen (AGT) (NM_000029) Human Recombinant Protein
E45H40174M5 20 ug
EUR 785.42

Rat Angiotensinogen ELISA
MBS495577-5x96Tests 5x96Tests
EUR 3945

Rat Angiotensinogen ELISA
MBS495577-96Tests 96Tests
EUR 855

Angiotensinogen Protein, Mouse, Recombinant (His Tag)
E45M52669M2-100 100 ug
EUR 1046.77

Angiotensinogen Protein, Human, Recombinant (His Tag)
E45H51255M2-50 50 ug
EUR 870.73

Recombinant Human Angiotensinogen Protein, His Tag
E40KMP1417 20ug
EUR 495

Angiotensinogen Protein, Human, Recombinant (His Tag)
MBS8120618-005mg 0.05mg
EUR 340

Angiotensinogen Protein, Human, Recombinant (His Tag)
MBS8120618-5x005mg 5x0.05mg
EUR 1380

Angiotensinogen Protein, Mouse, Recombinant (His Tag)
MBS8122693-01mg 0.1mg
EUR 395

Angiotensinogen Protein, Mouse, Recombinant (His Tag)
MBS8122693-5x01mg 5x0.1mg
EUR 1635

Recombinant Callithrix jacchus Angiotensinogen (AGT)
MBS1361828-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Callithrix jacchus Angiotensinogen (AGT)
MBS1361828-002mgEColi 0.02mg(E-Coli)
EUR 1010

Recombinant Callithrix jacchus Angiotensinogen (AGT)
MBS1361828-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Callithrix jacchus Angiotensinogen (AGT)
MBS1361828-01mgEColi 0.1mg(E-Coli)
EUR 1180

Recombinant Callithrix jacchus Angiotensinogen (AGT)
MBS1361828-01mgYeast 0.1mg(Yeast)
EUR 1270

Recombinant Human Angiotensinogen protein (C-6His)
CD02340-10ug 10ug
EUR 353
Description: Recombinant Human Serine Protease Inhibitor-clade A8 is produced by our Mammalian expression system and the target gene encoding Asp34-Ala485 is expressed with a 6His tag at the C-terminus.

Recombinant Human Angiotensinogen protein (C-6His)
CD02340-50ug 50ug
EUR 1035
Description: Recombinant Human Serine Protease Inhibitor-clade A8 is produced by our Mammalian expression system and the target gene encoding Asp34-Ala485 is expressed with a 6His tag at the C-terminus.

Recombinant Human Angiotensinogen, His-GST-tagged
AGT-2183H 10ug
EUR 238.4
Description: Avoid repeated freeze/thaw cycles. Store at 2-8-deg-C for one month. Aliquot and store at -80-deg-C for 12 months.

Recombinant Human Angiotensinogen/AGT Protein (His Tag)
PKSH032069-10ug 10ug
EUR 223
Description: Human

Recombinant Human Angiotensinogen/AGT Protein (His Tag)
PKSH032069-50ug 50ug
EUR 593
Description: Human

Rat Angiotensinogen CLIA Kit
MBS8426568-INQUIRE INQUIRE Ask for price

Rat angiotensinogen ELISA kit
55R-2262 1 kit
EUR 1427
Description: Rat angiotensinogen ELISA kit for use in research

Rat Angiotensinogen ELISA kit
E01A8964 96T
EUR 700
Description: ELISA

Rat Angiotensinogen ELISA kit
E02A0497-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-48wellsplate 48 wells plate
EUR 280

Rat Angiotensinogen ELISA kit
E02A0497-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Angiotensinogen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensinogen ELISA kit
E02A0497-96wellsplate 96 wells plate
EUR 405

Rat Angiotensinogen ELISA Kit
MBS039372-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Angiotensinogen ELISA Kit
MBS039372-48StripWells 48-Strip-Wells
EUR 550

Rat Angiotensinogen ELISA Kit
MBS039372-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Angiotensinogen ELISA Kit
MBS039372-96StripWells 96-Strip-Wells
EUR 765

Rat Angiotensinogen ELISA Kit
IRTAGTKT each
EUR 624
Description: Rat Angiotensinogen ELISA Kit

Rat Angiotensinogen ELISA Kit
MBS2881360-10x96StripWells 10x96-Strip-Wells
EUR 4080

Rat Angiotensinogen ELISA Kit
MBS2881360-48StripWells 48-Strip-Wells
EUR 390

Rat Angiotensinogen ELISA Kit
MBS2881360-5x96StripWells 5x96-Strip-Wells
EUR 2220

Rat Angiotensinogen ELISA Kit
MBS2881360-96StripWells 96-Strip-Wells
EUR 520

Rat Angiotensinogen ELISA Kit
MBS728265-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Angiotensinogen ELISA Kit
MBS728265-48StripWells 48-Strip-Wells
EUR 485

Rat Angiotensinogen ELISA Kit
MBS728265-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Angiotensinogen ELISA Kit
MBS728265-96StripWells 96-Strip-Wells
EUR 690

Rat Angiotensinogen ELISA Kit
MBS762162-10x96StripWells 10x96-Strip-Wells
EUR 3900

Rat Angiotensinogen ELISA Kit
MBS762162-48StripWells 48-Strip-Wells
EUR 340

Rat Angiotensinogen ELISA Kit
MBS762162-5x96StripWells 5x96-Strip-Wells
EUR 2045

Rat Angiotensinogen ELISA Kit
MBS762162-96StripWells 96-Strip-Wells
EUR 455

Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)
MBS1450817-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1320

Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)
MBS1450817-002mgEColi 0.02mg(E-Coli)
EUR 1010

Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)
MBS1450817-002mgYeast 0.02mg(Yeast)
EUR 1115

Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)
MBS1450817-01mgEColi 0.1mg(E-Coli)
EUR 1180

Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)
MBS1450817-01mgYeast 0.1mg(Yeast)
EUR 1270

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-10ug 10ug
EUR 242.4
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-1mg 1mg
EUR 2983.2
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-500ug 500ug
EUR 2106
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
CB56-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Angiotensinogen/Serpin A8/AGT (C-6His)
AP75516 1mg
EUR 3489

Rat Angiotensinogen (AGT) Protein
abx065353-100g 100 µg
EUR 337.5

An alanine-substitution scanning assay and sequence conservation evaluation elucidated that these porcine mAbs acknowledged two conserved epitopes on VP2: a linear epitope  in the N terminus and a conformational epitope involving residues Ok63, H65, L66, F67, D68 and L81 on two β-sheets (B-sheet and C-sheet) that trusted the integrity of VP2. Random parings of heavy and mild chains of the IgGs confirmed that the heavy chain is predominantly concerned in binding to antigen. The mild chain of porcine IgG contributes to the binding affinity towards an antigen and might operate as a help platform for antibody stability. In abstract, this research is the first to disclose the conserved antigenic profile of FMDV acknowledged by porcine B cells and offers a novel technique for analysing the antibody response in opposition to FMDV in its pure hosts (i.e. pigs) at the clonal stage.

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