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Category: Pigeon

Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS

Rapid and comprehensive monoclonal antibody Characterization using microfluidic CE-MS

Posted on September 4, 2021 by Cody

The identification and management of monoclonal antibody (mAb) vital high quality attributes (CQAs) is a key element of high quality by design (QbD). In this work, fast peptide mapping and native intact cost variants evaluation have been developed to comprehensively characterize and monitor mAb CQAs using a microfluidic capillary electrophoresis – mass spectrometry (CE-MS) platform.… Continue reading

Orally administered anti-eotaxin-1 monoclonal antibody is biologically active in the gut and alleviates immune-mediated hepatitis: A novel anti-inflammatory personalized therapeutic approach

Orally administered anti-eotaxin-1 monoclonal antibody is biologically active in the gut and alleviates immune-mediated hepatitis: A novel anti-inflammatory personalized therapeutic approach

Posted on September 4, 2021September 4, 2021 by Cody

Personalized therapies are designed to optimize the safety-to-efficacy ratio by deciding on sufferers with larger response charges based mostly on particular biomarkers. Inflammation performs an important position in the pathogenesis of non-alcoholic steatohepatitis (NASH), a standard liver dysfunction. Eotaxin-1 performs a task in innate and adaptive immune responses. High eotaxin-1 ranges are related to diabetes… Continue reading

Preferential Light-Chain Labeling of Native Monoclonal Antibodies Improves the Properties of Fluorophore Conjugates

Preferential Light-Chain Labeling of Native Monoclonal Antibodies Improves the Properties of Fluorophore Conjugates

Posted on September 3, 2021September 4, 2021 by Cody

Site particular labeling strategies have important potential to boost the properties of antibody conjugates. While studied extensively in the context of antibody-drug conjugates (ADCs), few research have examined the influence of homogenous labeling on the properties of antibody-fluorophore conjugates (AFCs). We report the utility of pentafluorophenyl (PFP) esters, which had beforehand been proven to be… Continue reading

Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations

Application of tunable resistive pulse sensing for the quantification of submicron particles in pharmaceutical monoclonal antibody preparations

Posted on August 28, 2021September 4, 2021 by Cody

Tunable resistive pulse sensing (TRPS, qNano Gold, IZON Ltd.) was investigated as a way to quantify submicron particles (SMPs) between 0.1 and 1 µm in options of biopharmaceuticals. To cut back pattern dilution, a spiking-in method was used so as to add the applicable quantity of electrolytes required for the measurement. For right particle quantification,… Continue reading

Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

Posted on August 28, 2021September 4, 2021 by Cody

Here, we evaluated the therapeutic potential of antibodies (Abs) focusing on cholinergic receptor nicotinic beta 2 subunit (CHRNB2) in gastric cancer. To examine the results of these Abs on malignant phenotypes in vitro and in mouse xenograft fashions, we generated gene knockouts by way of genome enhancing, carried out RNA interference-mediated knockdown of gene expression,… Continue reading

Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1

Selection and characterization of two monoclonal antibodies specific for the Aspergillus flavus major antigenic cell wall protein Aflmp1

Posted on August 4, 2021September 4, 2021 by Cody

Aspergillus flavus is a major fungal pathogen of vegetation and an opportunistic pathogen of people. In addition to the direct affect of an infection, it produces immunosuppressive and carcinogenic aflatoxins. The early detection of A. flavus is due to this fact essential to diagnose and monitor fungal an infection, to stop aflatoxin contamination of meals… Continue reading

Categories

  • 4 Host
  • 96T
  • apoptosis
  • array
  • Assay
  • Bacteria
  • Blocking
  • Combination of pembrolizumab and 125I attenuates the aggressiveness of non-small cell lung cancer.
  • Comparison of Efficacy of Topical Curcumin Gel with Triamcinolone-hyaluronidase Gel Individually and in Combination in the Treatment of Oral Submucous Fibrosis.
  • Comprehensive analysis of the long non-coding RNA-associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor.
  • GMO
  • Goat
  • Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma.
  • LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703.
  • Next-generation laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma.
  • Pig
  • Pigeon
  • Plant
  • plasmid
  • Plate
  • Prone en-bloc sacrectomy with proctectomy: A surgical approach to the inaccessible and hostile pelvis
  • Sleeve Gastrectomy: Surgical Technique, Outcomes, and Complications

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Recent Posts

  • Distributors of Lab PCR Assays
  • Compare recombinant lab reagents for research
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Breast Cancer Antibodies

Categories

  • 4 Host (6)
  • 96T (6)
  • apoptosis (7)
  • array (6)
  • Assay (6)
  • Bacteria (7)
  • Blocking (6)
  • Combination of pembrolizumab and 125I attenuates the aggressiveness of non-small cell lung cancer. (1)
  • Comparison of Efficacy of Topical Curcumin Gel with Triamcinolone-hyaluronidase Gel Individually and in Combination in the Treatment of Oral Submucous Fibrosis. (1)
  • Comprehensive analysis of the long non-coding RNA-associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor. (1)
  • GMO (6)
  • Goat (6)
  • Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma. (1)
  • LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703. (1)
  • Next-generation laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma. (1)
  • Pig (6)
  • Pigeon (6)
  • Plant (6)
  • plasmid (6)
  • Plate (5)
  • Prone en-bloc sacrectomy with proctectomy: A surgical approach to the inaccessible and hostile pelvis (1)
  • Sleeve Gastrectomy: Surgical Technique, Outcomes, and Complications (34)

Categories

  • 4 Host
  • 96T
  • apoptosis
  • array
  • Assay
  • Bacteria
  • Blocking
  • Combination of pembrolizumab and 125I attenuates the aggressiveness of non-small cell lung cancer.
  • Comparison of Efficacy of Topical Curcumin Gel with Triamcinolone-hyaluronidase Gel Individually and in Combination in the Treatment of Oral Submucous Fibrosis.
  • Comprehensive analysis of the long non-coding RNA-associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor.
  • GMO
  • Goat
  • Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma.
  • LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703.
  • Next-generation laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma.
  • Pig
  • Pigeon
  • Plant
  • plasmid
  • Plate
  • Prone en-bloc sacrectomy with proctectomy: A surgical approach to the inaccessible and hostile pelvis
  • Sleeve Gastrectomy: Surgical Technique, Outcomes, and Complications
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